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View Structure Prediction Details

Protein: Psi-PA
Organism: Drosophila melanogaster
Length: 716 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Psi-PA.

Description E-value Query
Range
Subject
Range
IF2B2_PONAB - Insulin-like growth factor 2 mRNA-binding protein 2 OS=Pongo abelii GN=IGF2BP2 PE=2 SV=1
IF2B2_PONPY - Insulin-like growth factor 2 mRNA-binding protein 2 - Pongo pygmaeus (Orangutan)
290.0 [0..9] [432..161]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGSGGGGG GGGGPGGASI TQAIAQAAAV AARLAASAGT SCEEQIRLPE SVAGAFMGRS  60
   61 SNDTITHIQA ESGVKVQVMQ DQDRVIMLRG QRDTVTKGRE MIQNMANRAG GGQVEVLLTI 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.30103
Match: 1e3hA
Description: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [121-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMPPPGPSGY PPYQEIMIPG AKVGLVIGKG GDTIKQLQEK TGAKMIIIQD GPNQELIKPL  60
   61 RISGEAQKIE HAKQMVLDLI AQKDAQGQQQ GGRGGGGGGG GPGMGFNNFN NGNGGESTEV 120
  121 FVPKIAVGVV IGKGGDMIRK IQTECGCKLQ FIQGKNDEMG DRRCVIQGTR QQVDDAKRTI 180
  181 DGLIENVMQR NGMNRNGNGG G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.0
Match: 2annA
Description: No description for 2annA was found.

Predicted Domain #3
Region A:
Residues: [322-424]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGPGGDSGNS NYGYGYGVNH AQGGREEITF LVPASKCGIV IGRGGETIKL INQQSGAHTE  60
   61 MDRNASNPPN EKLFKSKGTT DQVEAARQMI SEKINMELNV ISR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.522879
Match: 1j4wA
Description: Far upstream binding element, FBP, KH3 and KH4 domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.766407798661875 bayes_pls_golite062009
nucleic acid binding 0.1608635436815 bayes_pls_golite062009
RNA binding 0.0205643208063799 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [425-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPIGGGPGGG GGNSGGGQNN SHHNQQQGGY GGQNQMQGGD PNSGAGYQQQ PWGGPYGQQG  60
   61 WDPSGQQQQM AMANQGGSAA GGASGGQDYS AQWIEYYKQM GCHREAEMIE QQMKAKQAGG 120
  121 SSGPVQQQQP QQQQQSQQQT GGAGAGGADY SAQWAEYYRS VGKIEEAEAI EKTLKNKQNG 180
  181 SGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [608-716]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSSTPNPSQG GSGQQQPNPA AAAAAAAAAA AAAGGYGQSM TPTQYAQYSQ YYAAAAAAGG  60
   61 QPQGAPQPGG GQSGGPPGNY PGNYPGAGYG GYPGAPGQQQ QKSHKNDNH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle