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View Structure Prediction Details

Protein: yu-PC
Organism: Drosophila melanogaster
Length: 607 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for yu-PC.

Description E-value Query
Range
Subject
Range
gi|220947428, gi... - gi|220956880|gb|ACL90983.1| yu-PA [synthetic construct], gi|220947428|gb|ACL86257.1| yu-PA [syntheti...
yu-PA, FBpp03008... - The gene yu is referred to in FlyBase by the symbol Dmel\yu (CG3249, FBgn0029764). It is a protein_c...
369.0 [0..23] [607..1]

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Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLPCRCCCC SGKVTIFQYS AKMVSGRPLL YLSLPGVAFI LGVFWFRRRY KNCLDKPDDE  60
   61 DSSAINDSSI EPTVQARKAN GVLQNGKLPQ QSASKSMNIN GTLVNGSGSG SGSSSDEKDS 120
  121 PTTMLYGKSA PIKIQSNGRT SNGKHQQQID SEILKSKIQD AEHKTLCSID EDFENLSSPR 180
  181 DLPDSVNTRV SFYNRKATQK TVE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1x4nA
Description: Solution structure of KH domain in FUSE binding protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.63535971389028 bayes_pls_golite062009
RNA binding 1.16361089268969 bayes_pls_golite062009
nucleic acid binding 0.711581767271173 bayes_pls_golite062009
protein binding 0.427606060593007 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [204-378]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVVIKATRTP KISPENSFLD TNYTNKECEQ NNNCEPKEEP SKKEADQEEL EQDQEQTVLK  60
   61 EEVVDSNGNQ KRNVDAASPS LSICSVQSGD SGKGSSLPRS EATRVKTTYE FLFPISLIGH 120
  121 LYGRKRAFIN QIKAKTLASV SVGKNPYSGK VRICTIEGTE SEIDAALAMI RQRLP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.30103
Match: 1j4wA
Description: Far upstream binding element, FBP, KH3 and KH4 domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.63535971389028 bayes_pls_golite062009
RNA binding 1.16361089268969 bayes_pls_golite062009
nucleic acid binding 0.711581767271173 bayes_pls_golite062009
protein binding 0.427606060593007 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [379-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKRYPNFTMQ RIHFALPQTI VPLSTESLYN LQLKLIEGIN NDVVVSAVLS GSHIFIQHPL  60
   61 HPSHPSLPLL QKQLYDSYST MEAPLLPSLE LSAVCVIPIN DVWYRVQIVD TDPEDEERCV 120
  121 IKFLDFGGYM NVGFNTLRQI RTDFMNVPFQ STECILSNIE PIGGTWSIEA AEILNKLTKG 180
  181 IVLQAQVAGY NSHNLPEIFL FASLGPNNVI FINKELVGRK LAKWVEMSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.69897
Match: 2o4xA
Description: No description for 2o4xA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle