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View Structure Prediction Details

Protein: gi|193787288, gi...
Organism: Homo sapiens
Length: 252 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|193787288, gi....

Description E-value Query
Range
Subject
Range
gi|74001209 - gi|74001209|ref|XP_849295.1| PREDICTED: similar to calcipressin 1 isoform a isoform 1 [Canis familia...
0.0 [1..252] [1..249]
gi|114684002 - gi|114684002|ref|XP_001167915.1| PREDICTED: calcipressin 1 isoform 5 [Pan troglodytes]
0.0 [1..252] [1..252]
gi|74145094, gi|... - gi|74145094|dbj|BAE27416.1| unnamed protein product [Mus musculus], gi|33149234|gb|AAP96744.1| calci...
0.0 [1..252] [1..251]
gi|109065409 - gi|109065409|ref|XP_001088613.1| PREDICTED: similar to calcipressin 1 isoform a isoform 2 [Macaca mu...
0.0 [1..252] [1..249]
gi|89272039 - gi|89272039|emb|CAJ83182.1| Down syndrome critical region gene 1 [Xenopus tropicalis]
1.0E-88 [35..252] [16..235]
gi|50729949 - gi|50729949|ref|XP_416719.1| PREDICTED: similar to DSCR1-like protein [Gallus gallus]
2.0E-87 [36..252] [24..237]
RCAN1 - regulator of calcineurin 1
3.0E-87 [56..252] [1..197]
gi|27881773, gi|... - gi|27881773|gb|AAH44332.1| Dscr1-prov protein [Xenopus laevis], gi|148236400|ref|NP_001080661.1| Dow...
1.0E-86 [41..252] [18..231]

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Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDGVAGPQL GAAAEAAEAA EARARPGVTL RPFAPLSGAA EADEGGGDWS FIDCEMEEVD  60
   61 LQDLPSATIA CHLDPRVFVD GLCRAKFESL FRTYDKDITF QYFKSFKRVR INFSNPFSAA 120
  121 DARLQLHKTE FLGKEMKLYF AQTLHIGSSH LAPPNPDKQF LISPPASPPV G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.69897
Match: 1weyA
Description: Solution structure of RRM domain in calcipressin 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.11118333721636 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
RNA binding 2.45916448091535 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.9432590957792 bayes_pls_golite062009
hydrolase activity 1.69824301409862 bayes_pls_golite062009
mRNA binding 1.62410365165765 bayes_pls_golite062009
transcription regulator activity 1.24650529385826 bayes_pls_golite062009
DNA binding 1.23082363146877 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 0.426324573266235 bayes_pls_golite062009
sequence-specific DNA binding 0.0605038543305221 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [172-252]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WKQVEDATPV INYDLLYAIS KLGPGEKYEL HAATDTTPSV VVHVCESDQE KEEEEEMERM  60
   61 RRPKPKIIQT RRPEYTPIHL S

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle