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View Structure Prediction Details

Protein: AGAP7
Organism: Homo sapiens
Length: 663 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGAP7.

Description E-value Query
Range
Subject
Range
gi|113421490 - gi|113421490|ref|XP_001127197.1| PREDICTED: similar to centaurin, gamma-like family, member 1 isofor...
0.0 [1..663] [1..663]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNILTCRVH PSVSLEFDQQ QGSVCPSESE IYEAGAEDRM AGAPMAAAVQ PAEVTVEVGE  60
   61 DLHMHHVRDR EMPEALEFNP SANPEASTIF QRNSQT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVVEIRRSNC TNHVSTVHFS QQYSLCSTIF LDDSTAIQHY LTMTIISVTL EIPHHITQRD  60
   61 ADRSLSIPDE QLHSFAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 2bmjA
Description: Centaurin Gamma 1 (Human)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [174-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STVHITKNRN GGGSLNNYSS SIPSTPSTSQ EDPQFSVPPT ANTPTPVCKR SMRWSNLFTS  60
   61 EKGSDPDKER KAPENHAD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [252-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIGSGRAIPI KQGMLLKRSG KWLKTWKKKY VTLCSNGVLT YYSSLGDYMK YIHKKEIDLQ  60
   61 TSTIKVPGKW PSLATLACTP ISSSKSDGLS KDMDTGLGDS ICFSPSIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.39794
Match: 1u27A
Description: Triglycine variant of the ARNO Pleckstrin Homology Domain in complex with Ins(1,3,4,5)P4
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [360-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTIPKLNPP PSPHANKKKH LKKKSTNNFM IVSATGQTWH FEATTYEERD AWVQAIQSQI  60
   61 LASLQSCE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.52
Match: 1u5fA
Description: Crystal Structure of the PH Domain of SKAP-Hom with 8 Vector-derived N-terminal Residues
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [428-663]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSKSKSQLTS QSEAMALQSI QNMRGNAHCV DCETQNPKWA SLNLGVLMCI ECSGIHRSLG  60
   61 TRLSRVRSLE LDDWPVELRK VMSSIGNDLA NSIWEGSSQG RTKPTEKSTR EEKERWIRSK 120
  121 YEEKLFLAPL PCTELSLGQQ LLRATADEDL QTAILLLAHG SREEVNETCG EGDGCTALHL 180
  181 ACRKGNVVLA QLLIWYGVDV MARDAHGNTA LTYARQASSQ ECINVLLQYG CPDECV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 1dcqA
Description: Pyk2-associated protein beta; Pyk2-associated protein beta ARF-GAP domain
Matching Structure (courtesy of the PDB):

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