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View Structure Prediction Details

Protein: AGAP7
Organism: Homo sapiens
Length: 663 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGAP7.

Description E-value Query
Range
Subject
Range
gi|113421490 - gi|113421490|ref|XP_001127197.1| PREDICTED: similar to centaurin, gamma-like family, member 1 isofor...
0.0 [1..663] [1..663]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNILTCRVH PSVSLEFDQQ QGSVCPSESE IYEAGAEDRM AGAPMAAAVQ PAEVTVEVGE  60
   61 DLHMHHVRDR EMPEALEFNP SANPEASTIF QRNSQT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.420 0.484 regulation of GTPase activity a.1.1 Globin-like
View Download 0.236 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle

Predicted Domain #2
Region A:
Residues: [97-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVVEIRRSNC TNHVSTVHFS QQYSLCSTIF LDDSTAIQHY LTMTIISVTL EIPHHITQRD  60
   61 ADRSLSIPDE QLHSFAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 2bmjA
Description: Centaurin Gamma 1 (Human)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [174-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STVHITKNRN GGGSLNNYSS SIPSTPSTSQ EDPQFSVPPT ANTPTPVCKR SMRWSNLFTS  60
   61 EKGSDPDKER KAPENHAD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [252-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIGSGRAIPI KQGMLLKRSG KWLKTWKKKY VTLCSNGVLT YYSSLGDYMK YIHKKEIDLQ  60
   61 TSTIKVPGKW PSLATLACTP ISSSKSDGLS KDMDTGLGDS ICFSPSIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.39794
Match: 1u27A
Description: Triglycine variant of the ARNO Pleckstrin Homology Domain in complex with Ins(1,3,4,5)P4
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [360-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTIPKLNPP PSPHANKKKH LKKKSTNNFM IVSATGQTWH FEATTYEERD AWVQAIQSQI  60
   61 LASLQSCE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.52
Match: 1u5fA
Description: Crystal Structure of the PH Domain of SKAP-Hom with 8 Vector-derived N-terminal Residues
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [428-663]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSKSKSQLTS QSEAMALQSI QNMRGNAHCV DCETQNPKWA SLNLGVLMCI ECSGIHRSLG  60
   61 TRLSRVRSLE LDDWPVELRK VMSSIGNDLA NSIWEGSSQG RTKPTEKSTR EEKERWIRSK 120
  121 YEEKLFLAPL PCTELSLGQQ LLRATADEDL QTAILLLAHG SREEVNETCG EGDGCTALHL 180
  181 ACRKGNVVLA QLLIWYGVDV MARDAHGNTA LTYARQASSQ ECINVLLQYG CPDECV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 1dcqA
Description: Pyk2-associated protein beta; Pyk2-associated protein beta ARF-GAP domain
Matching Structure (courtesy of the PDB):

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