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View Structure Prediction Details

Protein: gi|119608164, gi...
Organism: Homo sapiens
Length: 898 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119608164, gi....

Description E-value Query
Range
Subject
Range
CIZ1 - CDKN1A interacting zinc finger protein 1
0.0 [1..898] [1..898]
gi|114626883 - gi|114626883|ref|XP_001155700.1| PREDICTED: Cip1-interacting zinc finger protein isoform 16 [Pan tro...
0.0 [1..898] [1..903]
gi|109110186 - gi|109110186|ref|XP_001112589.1| PREDICTED: similar to Cip1-interacting zinc finger protein isoform ...
0.0 [45..898] [38..891]

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Predicted Domain #1
Region A:
Residues: [1-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSQQQQQQL QQQQQQLQQL QQQQLQQQQL QQQQLLQLQQ LLQQSPPQAP LPMAVSRGLP  60
   61 PQQPQQPLLN LQGTNSASLL NGSMLQRALL LQQLQGLDQF AMPPATYDTA GLTMPTATLG 120
  121 NLRGYGMASP GLAAPSLTPP QLATPNLQQF FPQATRQSLL GPPPVGVPMN PSQFNLSGRN 180
  181 PQKQARTSSS TTPNRKDSSS QTMPVEDKSD PPEGS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [216-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEAAEPRMDT PEDQDLPPCP EDIAKEKRTP APEPEPCEAS ELPAKRLRSS EEPTEKEPPG  60
   61 QLQVKAQPQA RMTVPKQTQT PDLLPEALEA QVLPRFQPRV LQVQAQVQSQ TQPRIPSTDT 120
  121 QVQPKLQKQA QTQTSPEHLV LQQKQVQPQL QQEAEPQKQV QPQVQPQAHS QGPRQVQLQQ 180
  181 EAEPLKQVQP QVQPQAHSQP PRQVQLQLQK QVQTQTYPQV HTQAQPSVQP QEHPPAQVSV 240
  241 QPPEQTHEQP HTQPQVSLLA PE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [478-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTPVVVHVCG LEMPPDAVEA GGGMEKTLPE PVGTQVSMEE IQNESACGLD VGECENRARE  60
   61 MPGVWGAGGS LKVTILQSSD SRAFSTVPLT PVPRPSDSVS STPAATSTP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [587-685]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKQALQFFCY ICKASCSSQQ EFQDHMSEPQ HQQRLGEIQH MSQACLLSLL PVPRDVLETE  60
   61 DEEPPPRRWC NTCQLYYMGD LIQHRRTQDH KIAKQSLRP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [686-898]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FCTVCNRYFK TPRKFVEHVK SQGHKDKAKE LKSLEKEIAG QDEDHFITVD AVGCFEGDEE  60
   61 EEEDDEDEEE IEVEEELCKQ VRSRDISREE WKGSETYSPN TAYGVDFLVP VMGYICRICH 120
  121 KFYHSNSGAQ LSHCKSLGHF ENLQKYKAAK NPSPTTRPVS RRCAINARNA LTALFTSSGR 180
  181 PPSQPNTQDK TPSKVTARPS QPPLPRRSTR LKT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.07
Match: 1zu1A
Description: Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.64382899824662 bayes_pls_golite062009
nucleic acid binding 1.34250831649865 bayes_pls_golite062009
DNA binding 1.19507161856307 bayes_pls_golite062009
transcription regulator activity 0.973915756412119 bayes_pls_golite062009
transcription factor activity 0.134824658171215 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle