YRC Public Data Repository - Protein Structure Prediction

Protein:	EIF3B
Organism:	Homo sapiens
Length:	814 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EIF3B.

Description	E-value	Query Range	Subject Range
gi\|186464325, gi... - gi\|23128981\|ref\|ZP_00110817.1\| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi\|18668187...	577.0	[0..172]	[770..1170]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=... gi\|25530855 - pir\|\|AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)	569.0	[0..141]	[777..873]
gi\|109065848 - gi\|109065848\|ref\|XP_001086876.1\| PREDICTED: eukaryotic translation initiation factor 3, subunit 9 et...	562.0	[0..1]	[814..1]
gi\|75701503, gi\|... - gi\|75907778\|ref\|YP_322074.1\| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...	558.0	[0..172]	[770..1042]
EIF3B - eukaryotic translation initiation factor 3, subunit B	556.0	[0..1]	[814..1]
gi\|37523925, gi\|... - gi\|37523925\|ref\|NP_927302.1\| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi\|35214...	555.0	[0..141]	[738..577]

Back

Predicted Domain #1

Region A:
Residues: [1-162]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQDAENVAVP EAAEERAEPG QQQPAAEPPP AEGLLRPAGP GAPEAAGTEA SSEEVGIAEA  60
   61 GPESEVRTEP AAEAEAASGP SESPSPPAAE ELPGSHAEPP VPAQGEAPGE QARDERSDSR 120
  121 AQAVSEDAGG NEGRAAEAEP RALENGDADE PSFSDPEDFV DD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.69897
Match:	1y0fA
Description:	No description for 1y0fA was found.

Predicted Domain #2

Region A:
Residues: [163-251]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSEEELLGDV LKDRPQEADG IDSVIVVDNV PQVGPDRLEK LKNVIHKIFS KFGKITNDFY  60
   61 PEEDGKTKGY IFLEYASPAH AVDAVKNAD

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.16
Match:	2nlwA
Description:	No description for 2nlwA was found.

Predicted Domain #3

Region A:
Residues: [252-641]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYKLDKQHTF RVNLFTDFDK YMTISDEWDI PEKQPFKDLG NLRYWLEEAE CRDQYSVIFE  60
   61 SGDRTSIFWN DVKDPVSIEE RARWTETYVR WSPKGTYLAT FHQRGIALWG GEKFKQIQRF 120
  121 SHQGVQLIDF SPCERYLVTF SPLMDTQDDP QAIIIWDILT GHKKRGFHCE SSAHWPIFKW 180
  181 SHDGKFFARM TLDTLSIYET PSMGLLDKKS LKISGIKDFS WSPGGNIIAF WVPEDKDIPA 240
  241 RVTLMQLPTR QEIRVRNLFN VVDCKLHWQK NGDYLCVKVD RTPKGTQGVV TNFEIFRMRE 300
  301 KQVPVDVVEM KETIIAFAWE PNGSKFAVLH GEAPRISVSF YHVKNNGKIE LIKMFDKQQA 360
  361 NTIFWSPQGQ FVVLAGLRSM NGALAFVDTS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.30103
Match:	2ovpB
Description:	No description for 2ovpB was found.

Predicted Domain #4

Region A:
Residues: [642-741]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DCTVMNIAEH YMASDVEWDP TGRYVVTSVS WWSHKVDNAY WLWTFQGRLL QKNNKDRFCQ  60
   61 LLWRPRPPTL LSQEQIKQIK KDLKKYSKIF EQKDRLSQSK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.522879
Match:	2h9lA
Description:	No description for 2h9lA was found.

Predicted Domain #5

Region A:
Residues: [742-814]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASKELVERRR TMMEDFRKYR KMAQELYMEQ KNERLELRGG VDTDELDSNV DDWEEETIEF  60
   61 FVTEEIIPLG NQE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.862	a.70.1	N-terminal domain of the delta subunit of the F1F0-ATP synthase

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits