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View Structure Prediction Details

Protein: EIF3B
Organism: Homo sapiens
Length: 814 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EIF3B.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
577.0 [0..172] [770..1170]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
569.0 [0..141] [777..873]
gi|109065848 - gi|109065848|ref|XP_001086876.1| PREDICTED: eukaryotic translation initiation factor 3, subunit 9 et...
562.0 [0..1] [814..1]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
558.0 [0..172] [770..1042]
EIF3B - eukaryotic translation initiation factor 3, subunit B
556.0 [0..1] [814..1]
gi|37523925, gi|... - gi|37523925|ref|NP_927302.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35214...
555.0 [0..141] [738..577]

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Predicted Domain #1
Region A:
Residues: [1-162]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQDAENVAVP EAAEERAEPG QQQPAAEPPP AEGLLRPAGP GAPEAAGTEA SSEEVGIAEA  60
   61 GPESEVRTEP AAEAEAASGP SESPSPPAAE ELPGSHAEPP VPAQGEAPGE QARDERSDSR 120
  121 AQAVSEDAGG NEGRAAEAEP RALENGDADE PSFSDPEDFV DD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 1y0fA
Description: No description for 1y0fA was found.

Predicted Domain #2
Region A:
Residues: [163-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSEEELLGDV LKDRPQEADG IDSVIVVDNV PQVGPDRLEK LKNVIHKIFS KFGKITNDFY  60
   61 PEEDGKTKGY IFLEYASPAH AVDAVKNAD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.16
Match: 2nlwA
Description: No description for 2nlwA was found.

Predicted Domain #3
Region A:
Residues: [252-641]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYKLDKQHTF RVNLFTDFDK YMTISDEWDI PEKQPFKDLG NLRYWLEEAE CRDQYSVIFE  60
   61 SGDRTSIFWN DVKDPVSIEE RARWTETYVR WSPKGTYLAT FHQRGIALWG GEKFKQIQRF 120
  121 SHQGVQLIDF SPCERYLVTF SPLMDTQDDP QAIIIWDILT GHKKRGFHCE SSAHWPIFKW 180
  181 SHDGKFFARM TLDTLSIYET PSMGLLDKKS LKISGIKDFS WSPGGNIIAF WVPEDKDIPA 240
  241 RVTLMQLPTR QEIRVRNLFN VVDCKLHWQK NGDYLCVKVD RTPKGTQGVV TNFEIFRMRE 300
  301 KQVPVDVVEM KETIIAFAWE PNGSKFAVLH GEAPRISVSF YHVKNNGKIE LIKMFDKQQA 360
  361 NTIFWSPQGQ FVVLAGLRSM NGALAFVDTS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.30103
Match: 2ovpB
Description: No description for 2ovpB was found.

Predicted Domain #4
Region A:
Residues: [642-741]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DCTVMNIAEH YMASDVEWDP TGRYVVTSVS WWSHKVDNAY WLWTFQGRLL QKNNKDRFCQ  60
   61 LLWRPRPPTL LSQEQIKQIK KDLKKYSKIF EQKDRLSQSK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.522879
Match: 2h9lA
Description: No description for 2h9lA was found.

Predicted Domain #5
Region A:
Residues: [742-814]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASKELVERRR TMMEDFRKYR KMAQELYMEQ KNERLELRGG VDTDELDSNV DDWEEETIEF  60
   61 FVTEEIIPLG NQE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.862 a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.727 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.697 a.7.15 Description not found.
View Download 0.603 a.2.13 Description not found.
View Download 0.589 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.536 a.36.1 Signal peptide-binding domain
View Download 0.521 a.7.1 Spectrin repeat
View Download 0.513 a.7.1 Spectrin repeat
View Download 0.495 a.7.8 GAT domain
View Download 0.374 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.362 a.7.8 GAT domain
View Download 0.330 a.74.1 Cyclin-like
View Download 0.293 a.59.1 PAH2 domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle