YRC Public Data Repository - Protein Structure Prediction

Protein:	COPB1
Organism:	Homo sapiens
Length:	953 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COPB1.

Description	E-value	Query Range	Subject Range
gi\|73988865 - gi\|73988865\|ref\|XP_534069.2\| PREDICTED: similar to coatomer protein complex, subunit beta [Canis fam...	0.0	[1..953]	[102..1054]
COPB_MOUSE - Coatomer subunit beta OS=Mus musculus GN=Copb1 PE=1 SV=1	0.0	[1..953]	[1..953]
COPB_RAT - Coatomer subunit beta OS=Rattus norvegicus GN=Copb1 PE=1 SV=1	0.0	[1..953]	[1..953]
COPB_CHICK - Coatomer subunit beta OS=Gallus gallus GN=COPB1 PE=2 SV=1	0.0	[1..953]	[1..953]
gi\|55730026 - gi\|55730026\|emb\|CAH91738.1\| hypothetical protein [Pongo abelii] COPB_PONAB - Coatomer subunit beta OS=Pongo abelii GN=COPB1 PE=2 SV=1	0.0	[1..953]	[1..953]
gi\|114636308, gi... - gi\|114636310\|ref\|XP_001172109.1\| PREDICTED: coatomer protein complex, subunit beta isoform 7 [Pan tr...	0.0	[1..953]	[1..953]
COPB_BOVIN - Coatomer subunit beta OS=Bos taurus GN=COPB1 PE=1 SV=1	0.0	[1..953]	[1..953]
COPB1 - coatomer protein complex, subunit beta 1	0.0	[1..953]	[1..953]
gi\|68363464 - gi\|68363464\|ref\|XP_696952.1\| PREDICTED: similar to Coatomer protein complex, subunit beta 1 [Danio r...	0.0	[1..951]	[91..1041]

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Predicted Domain #1

Region A:
Residues: [1-608]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAAENVCYT LINVPMDSEP PSEISLKNDL EKGDVKSKTE ALKKVIIMIL NGEKLPGLLM  60
   61 TIIRFVLPLQ DHTIKKLLLV FWEIVPKTTP DGRLLHEMIL VCDAYRKDLQ HPNEFIRGST 120
  121 LRFLCKLKEA ELLEPLMPAI RACLEHRHSY VRRNAVLAIY TIYRNFEHLI PDAPELIHDF 180
  181 LVNEKDASCK RNAFMMLIHA DQDRALDYLS TCIDQVQTFG DILQLVIVEL IYKVCHANPS 240
  241 ERARFIRCIY NLLQSSSPAV KYEAAGTLVT LSSAPTAIKA AAQCYIDLII KESDNNVKLI 300
  301 VLDRLIELKE HPAHERVLQD LVMDILRVLS TPDLEVRKKT LQLALDLVSS RNVEELVIVL 360
  361 KKEVIKTNNV SEHEDTDKYR QLLVRTLHSC SVRFPDMAAN VIPVLMEFLS DNNEAAAADV 420
  421 LEFVREAIQR FDNLRMLIVE KMLEVFHAIK SVKIYRGALW ILGEYCSTKE DIQSVMTEIR 480
  481 RSLGEIPIVE SEIKKEAGEL KPEEEITVGP VQKLVTEMGT YATQSALSSS RPTKKEEDRP 540
  541 PLRGFLLDGD FFVAASLATT LTKIALRYVA LVQEKKKQNS FVAEAMLLMA TILHLGKSSL 600
  601 PKKPITDD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.39794
Match:	1w63B
Description:	AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [609-953]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVDRISLCLK VLSECSPLMN DIFNKECRQS LSHMLSAKLE EEKLSQKKES EKRNVTVQPD  60
   61 DPISFMQLTA KNEMNCKEDQ FQLSLLAAMG NTQRKEAADP LASKLNKVTQ LTGFSDPVYA 120
  121 EAYVHVNQYD IVLDVLVVNQ TSDTLQNCTL ELATLGDLKL VEKPSPLTLA PHDFANIKAN 180
  181 VKVASTENGI IFGNIVYDVS GAASDRNCVV LSDIHIDIMD YIQPATCTDA EFRQMWAEFE 240
  241 WENKVTVNTN MVDLNDYLQH ILKSTNMKCL TPEKALSGYC GFMAANLYAR SIFGEDALAN 300
  301 VSIEKPIHQG PDAAVTGHIR IRAKSQGMAL SLGDKINLSQ KKTSI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	69.69897
Match:	1pzdA
Description:	Structural Identification of a conserved appendage domain in the carboxyl-terminus of the COPI gamma-subunit.
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits