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View Structure Prediction Details

Protein: YQEG_ECOLI
Organism: Escherichia coli
Length: 409 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YQEG_ECOLI.

Description E-value Query
Range
Subject
Range
gi|68373624 - gi|68373624|ref|XP_692242.1| PREDICTED: similar to Cationic amino acid transporter 3 (CAT-3) (Solute...
246.0 [0..5] [385..975]
gi|91084137 - gi|91084137|ref|XP_969912.1| PREDICTED: similar to CG8475-PA, isoform A [Tribolium castaneum]
234.0 [0..7] [380..2481]
gi|47221082 - gi|47221082|emb|CAG12776.1| unnamed protein product [Tetraodon nigroviridis]
216.0 [0..4] [390..22]
gi|54641913, gi|... - gi|54641913|gb|EAL30662.1| GA20214-PA [Drosophila pseudoobscura], gi|125978255|ref|XP_001353160.1| G...
205.0 [0..5] [379..30]
CG7255-PH, CG7255-PF - This gene is referred to in FlyBase by the symbol Dmel\CG7255 (CG7255, FBgn0036493). It is a protein...
198.0 [0..5] [379..30]
gi|50746939 - gi|50746939|ref|XP_420685.1| PREDICTED: similar to cationic amino acid transporter-2 [Gallus gallus]
197.0 [0..5] [380..31]
gi|116181860, gi... - gi|88185855|gb|EAQ93323.1| hypothetical protein CHGG_01558 [Chaetomium globosum CBS 148.51], gi|1161...
179.0 [0..3] [389..109]
gi|46116238, gi|... - gi|46116238|ref|XP_384137.1| hypothetical protein FG03961.1 [Gibberella zeae PH-1], gi|42550586|gb|E...
178.0 [0..3] [383..75]

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Predicted Domain #1
Region A:
Residues: [1-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNIWSKEET LWSFALYGTA VGAGTLFLPI QLGSAGAVVL FITALVAWPL TYWPHKALCQ  60
   61 FILSSKTSAG EGITGAVTHY YGKKIGNLIT TLYFIAFFVV VLIYAVAITN SLTEQLAKHM 120
  121 VIDLRIRMLV SLGVVLILNL IFLMGRHATI RVMGFLVFPL IAYFLFLSIY LVGSWQPDLL 180
  181 TTQVEFNQNT LHQIWISIPV MVFAFSHTPI ISTFAIDRRE KYGEHAMDKC KKIMKVAYLI 240
  241 ICISVLFFVF SCLLSIPPSY IEAAKEEGVT ILSALSMLPN APAWLSISGI IVAVVAMSKS 300
  301 FLGTYFGVIE GATEVVKTTL QQVGVKKSRA FNRALSIMLV SLITFIVCCI NPNAISMIYA 360
  361 ISGPLIAMIL FIMPTLSTYL IPALKPWRSI GNLITLIVGI LCVSVMFFS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.4
Match: 2a65A
Description: Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
amine transmembrane transporter activity 5.15069657292327 bayes_pls_golite062009
amino acid transmembrane transporter activity 4.54752581624334 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 4.39427743642027 bayes_pls_golite062009
organic acid transmembrane transporter activity 4.356142166703 bayes_pls_golite062009
transporter activity 3.46503611631839 bayes_pls_golite062009
transmembrane transporter activity 3.34431027577801 bayes_pls_golite062009
substrate-specific transporter activity 3.08398439124803 bayes_pls_golite062009
active transmembrane transporter activity 2.98812190037621 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.96577701947757 bayes_pls_golite062009
ion transmembrane transporter activity 1.89542769737674 bayes_pls_golite062009
organic acid:sodium symporter activity 1.82263833070018 bayes_pls_golite062009
L-amino acid transmembrane transporter activity 1.79964917042361 bayes_pls_golite062009
cation transmembrane transporter activity 1.79923665576923 bayes_pls_golite062009
neutral amino acid transmembrane transporter activity 1.71764370341895 bayes_pls_golite062009
monoamine transmembrane transporter activity 1.59349600647168 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.37015067735708 bayes_pls_golite062009
symporter activity 1.31198147603118 bayes_pls_golite062009
solute:cation symporter activity 1.31198147603118 bayes_pls_golite062009
solute:sodium symporter activity 0.868753445363102 bayes_pls_golite062009
neurotransmitter:sodium symporter activity 0.658077875061275 bayes_pls_golite062009
binding 0.299468111884938 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle