YRC Public Data Repository - Protein Structure Prediction

Protein:	YKGA_ECOLI
Organism:	Escherichia coli
Length:	239 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKGA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|13359794, gi\|... - gi\|15829591\|ref\|NP_308364.1\| putative transcription regulator [Escherichia coli O157:H7], gi\|1335979... gi\|25350125, gi\|... - pir\|\|E85521 probable AraC-like transcription regulator ykgA [imported] - Escherichia coli (strain O1... gi\|12513100, gi\|... - gi\|15800013\|ref\|NP_286025.1\| putative AraC-like transcriptional regulator [Escherichia coli O157:H7 ... gi\|13359794, gi\|... - gi\|15829591\|ref\|NP_308364.1\| putative transcription regulator [Escherichia coli O157:H7 str. Sakai],...	205.0	[0..1]	[237..1]
gi\|117622578, gi... - gi\|117622578\|ref\|YP_851491.1\| putative transcriptional regulator [Escherichia coli APEC O1], gi\|1155... gi\|91209368, gi\|... - gi\|91209368\|ref\|YP_539354.1\| transcriptional regulator YkgA [Escherichia coli UTI89], gi\|91070942\|gb... gi\|226898918, gi... - gi\|237707708\|ref\|ZP_04538189.1\| transcriptional regulator YkgA [Escherichia sp. 3_2_53FAA], gi\|22689...	202.0	[0..1]	[237..1]
gi\|95133377, gi\|... - gi\|95930542\|ref\|ZP_01313277.1\| transcriptional regulator, AraC family [Desulfuromonas acetoxidans DS...	202.0	[0..16]	[238..5]
gi\|26106712, gi\|... - gi\|26246314\|ref\|NP_752353.1\| putative transcriptional regulator YkgA [Escherichia coli CFT073], gi\|2...	200.0	[0..1]	[237..1]
gi\|88917694, gi\|... - gi\|88935599\|ref\|ZP_01141229.1\| Helix-turn-helix, AraC type [Geobacter uraniumreducens Rf4], gi\|88917...	199.0	[0..9]	[237..4]
gi\|62129322, gi\|... - gi\|62181689\|ref\|YP_218106.1\| AraC family regulatory protein [Salmonella enterica subsp. enterica ser... gi\|224584975, gi... - gi\|224584975\|ref\|YP_002638774.1\| possible AraC-family transcriptional regulator [Salmonella enterica... gi\|194446792, gi... - gi\|194446792\|ref\|YP_002042440.1\| transcription activator, effector binding [Salmonella enterica subs...	198.0	[0..12]	[237..7]
gi\|84378045, gi\|... - gi\|84387184\|ref\|ZP_00990206.1\| putative transcriptional regulator (AraC family) [Vibrio splendidus 1...	197.0	[0..13]	[237..6]
gi\|78485568, gi\|... - gi\|78485568\|ref\|YP_391493.1\| AraC family transcriptional regulator [Thiomicrospira crunogena XCL-2],...	196.0	[0..17]	[237..12]
gi\|197244088, gi... - gi\|197265833\|ref\|ZP_03165907.1\| transcription activator, effector binding [Salmonella enterica subsp... gi\|205331279, gi... - gi\|205331279\|gb\|EDZ18043.1\| transcription activator, effector binding [Salmonella enterica subsp. en... gi\|16421731, gi\|... - gi\|16766475\|ref\|NP_462090.1\| putative regulatory protein [Salmonella typhimurium LT2], gi\|16421731\|g... lcl\|NC_016856.1_... - [gene=STM14_3847] [protein=putative regulatory protein] [protein_id=YP_005239346.1] [location=comple...	194.0	[0..12]	[237..7]
gi\|25350135, gi\|... - gi\|25350135\|pir\|\|AG0888 probable AraC-family transcription regulator STY3352 [imported] - Salmonella... gi\|213424350 - gi\|213424350\|ref\|ZP_03357174.1\| AraC family transcription regulator [Salmonella enterica subsp. ente... gi\|213647441 - gi\|213647441\|ref\|ZP_03377494.1\| AraC family transcription regulator [Salmonella enterica subsp. ente... gi\|29143438, gi\|... - gi\|29143438\|ref\|NP_806780.1\| AraC family transcription regulator [Salmonella enterica subsp. enteric... gi\|213973981 - gi\|213973981\|ref\|ZP_03401240.1\| AraC family transcription regulator [Salmonella enterica subsp. ente... gi\|16761951 - gi\|16761951\|ref\|NP_457568.1\| AraC family transcription regulator [Salmonella enterica subsp. enteric... gi\|214001849 - gi\|214001849\|ref\|ZP_03412584.1\| AraC family transcription regulator [Salmonella enterica subsp. ente... gi\|213027199 - gi\|213027199\|ref\|ZP_03341646.1\| AraC family transcription regulator [Salmonella enterica subsp. ente... gi\|213417333 - gi\|213417333\|ref\|ZP_03350475.1\| AraC family transcription regulator [Salmonella enterica subsp. ente...	194.0	[0..12]	[237..7]

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Predicted Domain #1

Region A:
Residues: [1-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYDKELTEN EMIRQKILQQ LLEWIECNLE HPISIEDIAQ KSGYSRRNIQ LLFRNFMHVP  60
   61 LGEYIRKRRL CRAAILVRLT AKSMLDIALS LHFDSQQSFS REFKKLFGCS PREYRHRDYW 120
  121 DLANIFPSFL IRQQQKTECR LINFPETPIF GNSFKYDIEV SNKSPDEEVK LRRHHLARCM 180
  181 KNFKTDIYFV STFEPSTKSV DLLTVETFAG TVCEYADMPK EWTTTRGLYD PTHVIWTQA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.69897
Match:	1d5yA
Description:	Rob transcription factor, N-terminal domain; Rob transcription factor, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.334577365229545	bayes_pls_golite062009
transcription regulator activity	0.0696342306231097	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: