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View Structure Prediction Details

Protein: YJJL_ECOLI
Organism: Escherichia coli
Length: 453 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJJL_ECOLI.

Description E-value Query
Range
Subject
Range
gi|67668083, gi|... - gi|67668083|ref|ZP_00465278.1| General substrate transporter:Major facilitator superfamily [Burkhold...
247.0 [0..2] [452..1004]
gi|91089229 - gi|91089229|ref|XP_968302.1| PREDICTED: similar to CG5304-PA [Tribolium castaneum]
241.0 [0..38] [453..577]
gi|68389434 - gi|68389434|ref|XP_691920.1| PREDICTED: similar to solute carrier family 17 (sodium-dependent inorga...
235.0 [0..2] [451..110]
gi|218202668 - gi|218202668|gb|EEC85095.1| hypothetical protein OsI_32467 [Oryza sativa Indica Group]
PHT44_ORYSJ - Probable anion transporter 4, chloroplastic OS=Oryza sativa subsp. japonica GN=PHT4;4 PE=2 SV=1
225.0 [0..12] [447..150]
gi|78495751, gi|... - gi|78495751|ref|ZP_00847969.1| Major facilitator superfamily MFS_1 [Rhodopseudomonas palustris BisB1...
225.0 [0..21] [446..430]
gi|92892758 - gi|92892758|gb|ABE91392.1| Major facilitator superfamily MFS_1 [Medicago truncatula]
222.0 [0..38] [447..176]
SLC17A8 - solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
221.0 [0..2] [451..42]
gi|31414749 - gi|31414749|gb|AAM50094.1| vesicular glutamate transporter 3 [Rattus norvegicus]
218.0 [0..2] [451..42]
VGLU3_MOUSE - Vesicular glutamate transporter 3 OS=Mus musculus GN=Slc17a8 PE=2 SV=1
218.0 [0..2] [451..42]

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Predicted Domain #1
Region A:
Residues: [1-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKENITIDP RSSFTPSSSA DIPVPPDGLV QRSTRIKRIQ TTAMLLLFFA AVINYLDRSS  60
   61 LSVANLTIRE ELGLSATEIG ALLSVFSLAY GIAQLPCGPL LDRKGPRLML GLGMFFWSLF 120
  121 QAMSGMVHNF TQFVLVRIGM GIGEAPMNPC GVKVINDWFN IKERGRPMGF FNAASTIGVA 180
  181 VSPPILAAMM LVMGWRGMFI TIGVLGIFLA IGWYMLYRNR EHVELTAVEQ AYLNAGSVNA 240
  241 RRDPLSFAEW RSLFRNRTMW GMMLGFSGIN YTAWLYLAWL PGYLQTAYNL DLKSTGLMAA 300
  301 IPFLFGAAGM LVNGYVTDWL VKGGMAPIKS RKICIIAGMF CSAAFTLIVP QATTSMTAVL 360
  361 LIGMALFCIH FAGTSCWGLI HVAVASRMTA SVGSIQNFAS FICASFAPII TGFIVDTTHS 420
  421 FRLALIICGC VTAAGALAYI FLVRQPINDP RKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.221849
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycerol transmembrane transporter activity 7.11654923455995 bayes_pls_golite062009
alcohol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
polyol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity 6.56587510931539 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.46247398538901 bayes_pls_golite062009
ion transmembrane transporter activity 4.58978526526921 bayes_pls_golite062009
cation transmembrane transporter activity 4.31967711223954 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
anion transmembrane transporter activity 3.94605227012838 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 2.52916479889426 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 2.32839532867295 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 2.32839532867295 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
phosphate transmembrane transporter activity 1.78662033436109 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 1.6904339767429 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
binding 0.818732184064642 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle