YRC Public Data Repository - Protein Structure Prediction

Protein:	SGBE_ECOLI
Organism:	Escherichia coli
Length:	231 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SGBE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|68195862, gi\|... - gi\|69245332\|ref\|ZP_00603376.1\| Class II aldolase/adducin, N-terminal [Enterococcus faecium DO], gi\|6... gi\|48825725 - ref\|ZP_00286965.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases [E...	257.0	[0..1]	[231..1]
gi\|52785817, gi\|... - gi\|52785817\|ref\|YP_091646.1\| L-ribulose-5-phosphate 4-epimerase [Bacillus licheniformis ATCC 14580],...	249.0	[0..1]	[231..1]
gi\|48870632, gi\|... - gi\|48870632\|ref\|ZP_00323352.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ...	248.0	[0..1]	[231..1]
gi\|19747447, gi\|... - gi\|19747447\|gb\|AAL96979.1\| putative L-ribulose 5-phosphate [Streptococcus pyogenes MGAS8232], gi\|197...	247.0	[0..2]	[231..26]
gi\|71801912, gi\|... - gi\|71902817\|ref\|YP_279620.1\| L-ribulose-5-phosphate 4-epimerase [Streptococcus pyogenes MGAS6180], g... gi\|28895055, gi\|... - gi\|28895055\|ref\|NP_801405.1\| L-ribulose-5-phosphate 4-epimerase [Streptococcus pyogenes SSI-1], gi\|2... gi\|21909676, gi\|... - gi\|21909676\|ref\|NP_663944.1\| L-ribulose-5-phosphate 4-epimerase [Streptococcus pyogenes MGAS315], gi...	247.0	[0..2]	[231..5]
gi\|15674384, gi\|... - gi\|15674384\|ref\|NP_268558.1\| L-ribulose-5-phosphate 4-epimerase [Streptococcus pyogenes M1 GAS], gi\|... gi\|71909967, gi\|... - gi\|71909967\|ref\|YP_281517.1\| L-ribulose-5-phosphate 4-epimerase [Streptococcus pyogenes MGAS5005], g...	246.0	[0..2]	[231..5]
gi\|94991658, gi\|... - gi\|94991658\|ref\|YP_599757.1\| L-ribulose-5-phosphate 4-epimerase [Streptococcus pyogenes MGAS2096], g...	246.0	[0..2]	[231..13]
gi\|94543172, gi\|... - gi\|94989664\|ref\|YP_597764.1\| L-ribulose-5-phosphate 4-epimerase [Streptococcus pyogenes MGAS10270], ... gi\|94993555, gi\|... - gi\|94993555\|ref\|YP_601653.1\| L-ribulose-5-phosphate 4-epimerase [Streptococcus pyogenes MGAS10750], ...	245.0	[0..2]	[231..13]
gi\|50913545, gi\|... - gi\|50913545\|ref\|YP_059517.1\| L-ribulose-5-phosphate 4-epimerase [Streptococcus pyogenes MGAS10394], ... gi\|94987786, gi\|... - gi\|94987786\|ref\|YP_595887.1\| L-ribulose-5-phosphate 4-epimerase [Streptococcus pyogenes MGAS9429], g...	245.0	[0..2]	[231..13]
gi\|12721601, gi\|... - gi\|15603109\|ref\|NP_246181.1\| L-ribulose-5-phosphate 4-epimerase [Pasteurella multocida subsp. multoc...	245.0	[0..1]	[231..13]

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Predicted Domain #1

Region A:
Residues: [1-231]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEQLKADVL AANLALPAHH LVTFTWGNVS AVDETRQWMV IKPSGVEYDV MTADDMVVVE  60
   61 IASGKVVEGS KKPSSDTPTH LALYRRYAEI GGIVHTHSRH ATIWSQAGLD LPAWGTTHAD 120
  121 YFYGAIPCTR QMTAEEINGE YEYQTGEVII ETFEERGRSP AQIPAVLVHS HGPFAWGKNA 180
  181 ADAVHNAVVL EECAYMGLFS RQLAPQLPAM QNELLDKHYL RKHGANAYYG Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	63.522879
Match:	1jdiA
Description:	L-ribulose-5-phosphate 4-epimerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
L-ribulose-phosphate 4-epimerase activity	3.50507333471987	bayes_pls_golite062009
L-fuculose-phosphate aldolase activity	2.43949811564444	bayes_pls_golite062009
catalytic activity	1.9511172460719	bayes_pls_golite062009
aldehyde-lyase activity	1.08084403816388	bayes_pls_golite062009
lyase activity	0.77829514510632	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.42493443904865	bayes_pls_golite062009
carbon-carbon lyase activity	0.2178091782272	bayes_pls_golite062009
racemase and epimerase activity	0.15063402811264	bayes_pls_golite062009
isomerase activity	0.0458367676418101	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: