| Protein: | SRGAP1 |
| Organism: | Homo sapiens |
| Length: | 1085 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRGAP1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1085] | [1..1085] |
|
|
0.0 | [1..1085] | [1..1085] |
|
|
0.0 | [1..1085] | [1..1083] |
|
|
0.0 | [1..1085] | [1..1085] |
|
|
0.0 | [23..1085] | [24..1104] |
|
Region A: Residues: [1-341] |
1 11 21 31 41 51
| | | | | |
1 MSTPSRFKKD KEIIAEYESQ VKEIRAQLVE QQKCLEQQTE MRVQLLQDLQ DFFRKKAEIE 60
61 TEYSRNLEKL AERFMAKTRS TKDHQQYKKD QNLLSPVNCW YLLLNQVRRE SKDHATLSDI 120
121 YLNNVIMRFM QISEDSTRMF KKSKEIAFQL HEDLMKVLNE LYTVMKTYHM YHAESISAES 180
181 KLKEAEKQEE KQIGRSGDPV FHIRLEERHQ RRSSVKKIEK MKEKRQAKYS ENKLKSIKAR 240
241 NEYLLTLEAT NASVFKYYIH DLSDLIDCCD LGYHASLNRA LRTYLSAEYN LETSRHEGLD 300
301 IIENAVDNLE PRSDKQRFME MYPAAFCPPM KFEFQSHMGD E
|
| Detection Method: |  |
| Confidence: | 19.0 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [342-421] |
1 11 21 31 41 51
| | | | | |
1 VCQVSAQQPV QAELMLRYQQ LQSRLATLKI ENEEVKKTTE ATLQTIQDMV TIEDYDVSEC 60
61 FQHSRSTESV KSTVSETYLS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [422-691] |
1 11 21 31 41 51
| | | | | |
1 KPSIAKRRAN QQETEQFYFM KLREYLEGSN LITKLQAKHD LLQRTLGEGH RAEYMTTRPP 60
61 NVPPKPQKHR KSRPRSQYNT KLFNGDLETF VKDSGQVIPL IVESCIRFIN LYGLQHQGIF 120
121 RVSGSQVEVN DIKNSFERGE NPLADDQSNH DINSVAGVLK LYFRGLENPL FPKERFNDLI 180
181 SCIRIDNLYE RALHIRKLLL TLPRSVLIVM RYLFAFLNHL SQYSDENMMD PYNLAICFGP 240
241 TLMPVPEIQD QVSCQAHVNE IIKTIIIHHE
|
| Detection Method: | |
| Confidence: | 31.0 |
| Match: | 1xa6A |
| Description: | Crystal Structure of the Human Beta2-Chimaerin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| Rho GTPase activator activity | 4.58620967349979 | bayes_pls_golite062009 |
| Rac GTPase activator activity | 4.48279904625182 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.42802398019084 | bayes_pls_golite062009 |
| binding | 2.79128751898373 | bayes_pls_golite062009 |
| GTPase regulator activity | 2.70614727793157 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 2.68579854252375 | bayes_pls_golite062009 |
| actin binding | 2.59114492135519 | bayes_pls_golite062009 |
| tubulin binding | 2.31518443151057 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 2.06038764955701 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.9750017471254 | bayes_pls_golite062009 |
| small GTPase regulator activity | 1.95738547986197 | bayes_pls_golite062009 |
| motor activity | 1.59872328451279 | bayes_pls_golite062009 |
| microtubule binding | 1.39416664093439 | bayes_pls_golite062009 |
| Rho GTPase binding | 1.34980300847466 | bayes_pls_golite062009 |
| protein binding | 1.29100556128076 | bayes_pls_golite062009 |
| molecular transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| signal transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 1.09070479183477 | bayes_pls_golite062009 |
| transcription regulator activity | 1.08577758274384 | bayes_pls_golite062009 |
| Rho guanyl-nucleotide exchange factor activity | 0.967362611034944 | bayes_pls_golite062009 |
| Ras guanyl-nucleotide exchange factor activity | 0.958295643211986 | bayes_pls_golite062009 |
| actin filament binding | 0.937704425867942 | bayes_pls_golite062009 |
| GTPase activator activity | 0.717730683557543 | bayes_pls_golite062009 |
| nucleic acid binding | 0.480348726111787 | bayes_pls_golite062009 |
| receptor activity | 0.434186339265983 | bayes_pls_golite062009 |
| DNA binding | 0.418154636457321 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.38335246506929 | bayes_pls_golite062009 |
| enzyme activator activity | 0.298334474872045 | bayes_pls_golite062009 |
| microfilament motor activity | 0.0746966011130201 | bayes_pls_golite062009 |
|
Region A: Residues: [692-935] |
1 11 21 31 41 51
| | | | | |
1 TIFPDAKELD GPVYEKCMAG DDYCDSPYSE HGTLEEVDQD AGTEPHTSED ECEPIEAIAK 60
61 FDYVGRSARE LSFKKGASLL LYHRASEDWW EGRHNGIDGL VPHQYIVVQD MDDTFSDTLS 120
121 QKADSEASSG PVTEDKSSSK DMNSPTDRHP DGYLARQRKR GEPPPPVRRP GRTSDGHCPL 180
181 HPPHALSNSS VDLGSPSLAS HPRGLLQNRG LNNDSPERRR RPGHGSLTNI SRHDSLKKID 240
241 SPPI
|
| Detection Method: | |
| Confidence: | 3.86 |
| Match: | 1ng2A |
| Description: | p47pox (neutrophil cytosolic factor 1) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [936-1015] |
1 11 21 31 41 51
| | | | | |
1 RRSTSSGQYT GFNDHKPLDP ETIAQDIEET MNTALNELRE LERQSTAKHA PDVVLDTLEQ 60
61 VKNSPTPATS TESLSPLHNV
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1016-1085] |
1 11 21 31 41 51
| | | | | |
1 ALRSSEPQIR RSTSSSSDTM STFKPMVAPR MGVQLKPPAL RPKPAVLPKT NPTIGPAPPP 60
61 QGPTDKSCTM
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
