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View Structure Prediction Details

Protein: TFS_THECE
Organism: Thermococcus celer
Length: 110 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFS_THECE.

Description E-value Query
Range
Subject
Range
gi|66735410 - gi|66735410|gb|AAY53887.1| DNA-dependent RNA polymerase subunit M [Thermococcus thioreducens]
130.0 [0..1] [110..1]
gi|1076155 - gi|1076155|pir||A55263 transcription-associated protein - Thermococcus celer
127.0 [0..1] [110..1]
gi|57640468, gi|... - gi|57640468|ref|YP_182946.1| DNA-directed RNA polymerase subunit M [Thermococcus kodakarensis KOD1],...
123.0 [0..1] [110..1]
gi|74004298 - gi|74004298|ref|XP_545465.2| PREDICTED: similar to zinc ribbon domain containing, 1 [Canis familiari...
119.0 [0..1] [109..389]
gi|18893037, gi|... - gi|18977358|ref|NP_578715.1| DNA-directed RNA polymerase subunit M [Pyrococcus furiosus DSM 3638], g...
119.0 [0..1] [110..2]
gi|5458798, gi|7... - pir||H75048 DNA-directed RNA polymerase (EC 2.7.7.6) chain M PAB1464 - Pyrococcus abyssi (strain Ors...
gi|5458798, gi|1... - gi|5458798|emb|CAB50285.1| tfs archaeal transcription factor S [Pyrococcus abyssi GE5], gi|14521579|...
118.0 [0..1] [110..2]
gi|3257072, gi|1... - gi|3257072|dbj|BAA29755.1| 110aa long hypothetical transcription-associated protein [Pyrococcus hori...
gi|7447275 - pir||A71112 probable transcription-associated protein - Pyrococcus horikoshii
117.0 [0..1] [110..2]
gi|46438863, gi|... - gi|68477862|ref|XP_717083.1| hypothetical protein CaO19.12820 [Candida albicans SC5314], gi|68477699...
orf19.12820, orf... - RPC11 CGDID:CAL0004345 Assembly 19, Contig19-10225 (127260, 127595) CDS, translated using codon tabl...
115.0 [0..1] [108..2]
gi|58269278, gi|... - gi|58269278|ref|XP_571795.1| RNA polymerase III smallest subunit [Cryptococcus neoformans var. neofo...
113.0 [0..1] [108..1]

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Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFCPKCGNL MLPDRKRKVW VCRSCGYEEP FDEEKDREKT VIKQEVKHKP DEGIVVIEQD  60
   61 L

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 27.853872
Match: PF02150.7
Description: No description for PF02150.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [62-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTLPTTKITC PKCGNDTAYW WEMQTRAGDE PSTIFYKCTK CGHTWRSYE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1qypA
Description: THERMOCOCCUS CELER RPB9, NMR, 25 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA-directed RNA polymerase activity 8.87472871386782 bayes_pls_golite062009
RNA polymerase activity 8.87472871386782 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 7.01586910046629 bayes_pls_golite062009
nucleotidyltransferase activity 6.30881681756207 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.66342402708121 bayes_pls_golite062009
transferase activity 3.6513313586587 bayes_pls_golite062009
transcription regulator activity 3.36253105801209 bayes_pls_golite062009
binding 2.58311326284197 bayes_pls_golite062009
transcription elongation regulator activity 2.03339710864117 bayes_pls_golite062009
nucleic acid binding 1.8086747972572 bayes_pls_golite062009
DNA binding 1.76634962183736 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.57988053581899 bayes_pls_golite062009
DNA primase activity 1.01743034310838 bayes_pls_golite062009
protein binding 0.764662055834369 bayes_pls_golite062009
catalytic activity 0.434839928397784 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle