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View Structure Prediction Details

Protein: PANC_THEMA
Organism: Thermotoga maritima
Length: 280 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PANC_THEMA.

Description E-value Query
Range		 Subject
Range
PANC_THENE - Pantothenate synthetase OS=Thermotoga neapolitana GN=panC PE=3 SV=1
 463.0 [0..1] [280..1]
gi|196253301, gi... - gi|196253301|ref|ZP_03151934.1| pantoate--beta-alanine ligase [Clostridium thermocellum DSM 4150], g...
PANC_CLOTH - Pantothenate synthetase OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NC...
 443.0 [0..1] [279..1]
PANC_MOOTA - Pantothenate synthetase OS=Moorella thermoacetica (strain ATCC 39073) GN=panC PE=3 SV=1
 440.0 [0..1] [279..1]
gi|98661990 - gi|98661990|dbj|GAA01058.1| unnamed protein product [Pelotomaculum thermopropionicum SI]
 437.0 [0..1] [280..5]
PANC_DESHD - Pantothenate synthetase OS=Desulfitobacterium hafniense (strain DCB-2 / DSM 10664) GN=panC PE=3 SV=1
PANC_DESHY - Pantothenate synthetase OS=Desulfitobacterium hafniense (strain Y51) GN=panC PE=3 SV=1
 431.0 [0..1] [279..1]
gi|27262518 - gi|27262518|gb|AAN87540.1| Pantoate--beta-alanine ligase [Heliobacillus mobilis]
 428.0 [0..1] [278..27]
PANC_THEPX - Pantothenate synthetase OS=Thermoanaerobacter sp. (strain X514) GN=panC PE=3 SV=1
gi|242232266, gi... - gi|242256189|ref|ZP_04801084.1| pantoate/beta-alanine ligase [Thermoanaerobacter sp. X513], gi|24223...
 428.0 [0..1] [280..1]
PANC_PSEPF - Pantothenate synthetase OS=Pseudomonas fluorescens (strain Pf0-1) GN=panC PE=3 SV=1
 427.0 [0..1] [279..1]
PANC_THEP3 - Pantothenate synthetase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) GN=panC PE=...
gi|241903489, gi... - gi|241903489|ref|ZP_04788212.1| pantoate/beta-alanine ligase [Thermoanaerobacter brockii subsp. finn...
 427.0 [0..1] [280..1]
PANC_AQUAE - Pantothenate synthetase OS=Aquifex aeolicus (strain VF5) GN=panC PE=3 SV=1
PANC_AQUAE - Pantothenate synthetase OS=Aquifex aeolicus GN=panC PE=3 SV=1
 427.0 [0..3] [276..4]

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Predicted Domain #1
Region A:
Residues: [1-280] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIIETIEEM KKFSEEMREK KKTIGFVPTM GYLHEGHLSL VRRARAENDV VVVSIFVNPT  60
   61 QFGPNEDYER YPRDFERDRK LLEKENVDCI FHPSVEEMYP PDFSTYVEET KLSKHLCGRS 120
  121 RPGHFRGVCT VVTKLFNIVK PHRAYFGQKD AQQFRVLRRM VRDLNMDVEM IECPIVREPD 180
  181 GLAMSSRNVY LSPEERQQAL SLYQSLKIAE NLYLNGERDA EKIKEEMIKH LSRFDKVKID 240
  241 YVEIVDEETL EPVEKIDRKV IVAVAAWVGN ARLIDNTILG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 117.0
Match: 1ihoA
Description: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming aminoacyl-tRNA and related compounds 5.66762539052452 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 5.66762539052452 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 5.65398773296369 bayes_pls_golite062009
ligase activity 4.61911329839139 bayes_pls_golite062009
pantoate-beta-alanine ligase activity 2.65346774278189 bayes_pls_golite062009
catalytic activity 2.37674226834122 bayes_pls_golite062009
glutamate-tRNA ligase activity 2.21467185575886 bayes_pls_golite062009
nucleic acid binding 1.64840822019417 bayes_pls_golite062009
methionine-tRNA ligase activity 1.59260025359667 bayes_pls_golite062009
tyrosine-tRNA ligase activity 1.47110858685627 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.38579849961344 bayes_pls_golite062009
pantetheine-phosphate adenylyltransferase activity 1.25694296916214 bayes_pls_golite062009
binding 1.11291710031577 bayes_pls_golite062009
adenylyltransferase activity 1.08055019963499 bayes_pls_golite062009
transferase activity 1.06817715108743 bayes_pls_golite062009
tryptophan-tRNA ligase activity 0.725178047574893 bayes_pls_golite062009
arginine-tRNA ligase activity 0.722005407734432 bayes_pls_golite062009
nicotinate-nucleotide adenylyltransferase activity 0.692499879958128 bayes_pls_golite062009
nicotinamide-nucleotide adenylyltransferase activity 0.567882194154248 bayes_pls_golite062009
nucleotidyltransferase activity 0.564359271862248 bayes_pls_golite062009
cysteine-tRNA ligase activity 0.430902479559327 bayes_pls_golite062009
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