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View Structure Prediction Details

Protein: NAGB_ECOLI
Organism: Escherichia coli
Length: 266 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAGB_ECOLI.

Description E-value Query
Range
Subject
Range
gi|114593868 - gi|114593868|ref|XP_001143245.1| PREDICTED: similar to glucosamine-6-phosphate deaminase 2 variant [...
345.0 [0..1] [266..124]
gi|148226212, gi... - gi|38014417|gb|AAH60459.1| MGC68566 protein [Xenopus laevis], gi|148226212|ref|NP_001083469.1| hypot...
343.0 [0..1] [266..1]
gi|73974964 - gi|73974964|ref|XP_849417.1| PREDICTED: similar to glucosamine-6-phosphate deaminase 2 isoform 1 [Ca...
342.0 [0..1] [266..1]
GNPI2_BOVIN - Glucosamine-6-phosphate isomerase 2 OS=Bos taurus GN=GNPDA2 PE=2 SV=1
341.0 [0..1] [266..1]
GNPI1_MOUSE, GNP... - Glucosamine-6-phosphate isomerase - Mus musculus (Mouse), Glucosamine-6-phosphate isomerase 1 OS=Mus...
340.0 [0..1] [266..1]
GNPDA2 - glucosamine-6-phosphate deaminase 2
ENSPTRT00000029877 - null
340.0 [0..1] [266..1]

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Predicted Domain #1
Region A:
Residues: [1-266]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLIPLTTAE QVGKWAARHI VNRINAFKPT ADRPFVLGLP TGGTPMTTYK ALVEMHKAGQ  60
   61 VSFKHVVTFN MDEYVGLPKE HPESYYSFMH RNFFDHVDIP AENINLLNGN APDIDAECRQ 120
  121 YEEKIRSYGK IHLFMGGVGN DGHIAFNEPA SSLASRTRIK TLTHDTRVAN SRFFDNDVNQ 180
  181 VPKYALTVGV GTLLDAEEVM ILVLGSQKAL ALQAAVEGCV NHMWTISCLQ LHPKAIMVCD 240
  241 EPSTMELKVK TLRYFNELEA ENIKGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.69897
Match: 1cd5A
Description: Glucosamine 6-phosphate deaminase/isomerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glucosamine-6-phosphate deaminase activity 4.20201419087614 bayes_pls_golite062009
intramolecular oxidoreductase activity 2.15381323621148 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses 1.65800801564277 bayes_pls_golite062009
catalytic activity 1.31732715713197 bayes_pls_golite062009
ribose-5-phosphate isomerase activity 1.21538742769205 bayes_pls_golite062009
nucleic acid binding 1.15193795385115 bayes_pls_golite062009
binding 0.790197816513984 bayes_pls_golite062009
transcription regulator activity 0.527142798518238 bayes_pls_golite062009
6-phosphogluconolactonase activity 0.480819049634739 bayes_pls_golite062009
DNA binding 0.465566131334457 bayes_pls_golite062009
isomerase activity 0.102415560220489 bayes_pls_golite062009
protein binding 0.0458232930850621 bayes_pls_golite062009

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