YRC Public Data Repository - Protein Structure Prediction

Protein:	MRR_ECOLI
Organism:	Escherichia coli
Length:	304 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|91214002, gi\|... - gi\|91214002\|ref\|YP_543988.1\| Mrr protein [Escherichia coli UTI89], gi\|91075576\|gb\|ABE10457.1\| Mrr pr... gi\|117626663, gi... - gi\|117626663\|ref\|YP_859986.1\| methylated adenine and cytosine restriction protein [Escherichia coli ...	288.0	[0..1]	[304..1]
gi\|75812373, gi\|... - gi\|75812373\|ref\|YP_319992.1\| restriction endonuclease [Anabaena variabilis ATCC 29413], gi\|75705129\|...	286.0	[0..1]	[303..1]
gi\|86608284 - gi\|86608284\|ref\|YP_477046.1\| mrr restriction system protein [Cyanobacteria bacterium Yellowstone B-P... gi\|86608284, gi\|... - gi\|86608284\|ref\|YP_477046.1\| mrr restriction system protein [Synechococcus sp. JA-2-3B'a(2-13)], gi\|...	284.0	[0..1]	[304..1]
gi\|17233148, gi\|... - gi\|17233148\|ref\|NP_490238.1\| mrr restriction system protein [Nostoc sp. PCC 7120], gi\|17135670\|dbj\|B... gi\|25348829 - pir\|\|AD2494 mrr restriction system protein [imported] - Nostoc sp. (strain PCC 7120) plasmid pCC712...	283.0	[0..1]	[303..1]
gi\|88601780, gi\|... - gi\|88601780\|ref\|YP_501958.1\| restriction endonuclease [Methanospirillum hungatei JF-1], gi\|88187242\|...	277.0	[0..1]	[304..1]
gi\|19918685, gi\|... - gi\|20093325\|ref\|NP_619400.1\| Mrr restriction system protein [Methanosarcina acetivorans C2A], gi\|199...	274.0	[0..1]	[304..1]
gi\|7473157 - pir\|\|C75500 mrr restriction system protein - Deinococcus radiodurans (strain R1) gi\|15805614, gi\|... - gi\|6458285\|gb\|AAF10167.1\|AE001917_4 mrr restriction system protein [Deinococcus radiodurans R1], gi\|...	272.0	[0..1]	[304..1]
gi\|213864871 - gi\|213864871\|ref\|ZP_03386990.1\| mrr restriction system protein [Salmonella enterica subsp. enterica ... gi\|213648686 - gi\|213648686\|ref\|ZP_03378739.1\| mrr restriction system protein [Salmonella enterica subsp. enterica ... gi\|25348828, gi\|... - gi\|25348828\|pir\|\|AE1069 mrr restriction system protein [imported] - Salmonella enterica subsp. enter... gi\|213428391 - gi\|213428391\|ref\|ZP_03361141.1\| mrr restriction system protein [Salmonella enterica subsp. enterica ... gi\|168821020, gi... - gi\|205342331\|gb\|EDZ29095.1\| Mrr restriction system protein [Salmonella enterica subsp. enterica sero... gi\|16763333 - gi\|16763333\|ref\|NP_458950.1\| mrr restriction system protein [Salmonella enterica subsp. enterica ser... gi\|29144811, gi\|... - gi\|29144811\|ref\|NP_808153.1\| mrr restriction system protein [Salmonella enterica subsp. enterica ser... gi\|213999648 - gi\|213999648\|ref\|ZP_03410383.1\| mrr restriction system protein [Salmonella enterica subsp. enterica ...	272.0	[0..1]	[304..1]
gi\|197365234, gi... - gi\|197365234\|ref\|YP_002144871.1\| mrr restriction system protein [Salmonella enterica subsp. enterica... gi\|56416311, gi\|... - gi\|56416311\|ref\|YP_153386.1\| mrr restriction system protein [Salmonella enterica subsp. enterica ser...	271.0	[0..1]	[304..1]
gi\|205332964, gi... - gi\|205332964\|gb\|EDZ19728.1\| Mrr restriction system protein [Salmonella enterica subsp. enterica sero... gi\|168243975, gi... - gi\|205336958\|gb\|EDZ23722.1\| Mrr restriction system protein [Salmonella enterica subsp. enterica sero... gi\|205330322, gi... - gi\|205330322\|gb\|EDZ17086.1\| Mrr restriction system protein [Salmonella enterica subsp. enterica sero... lcl\|NC_016856.1_... - [gene=mrr] [protein=restriction endonuclease] [protein_id=YP_005240866.1] [location=4797299..4798213... gi\|197261719, gi... - gi\|197261719\|ref\|ZP_03161793.1\| Mrr restriction system protein [Salmonella enterica subsp. enterica ... gi\|16423094, gi\|... - gi\|16767771\|ref\|NP_463386.1\| restriction endonuclease [Salmonella typhimurium LT2], gi\|16423094\|gb\|A... gi\|194406907, gi... - gi\|194448603\|ref\|YP_002048550.1\| Mrr restriction system protein [Salmonella enterica subsp. enterica... gi\|194470597, gi... - gi\|194470597\|ref\|ZP_03076581.1\| Mrr restriction system protein [Salmonella enterica subsp. enterica ...	270.0	[0..1]	[304..1]

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Predicted Domain #1

Region A:
Residues: [1-165]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVPTYDKFI EPVLRYLATK PEGAAARDVH EAAADALGLD DSQRAKVITS GQLVYKNRAG  60
   61 WAHDRLKRAG LSQSLSRGKW CLTPAGFDWV ASHPQPMTEQ ETNHLAFAFV NVKLKSRPDA 120
  121 VDLDPKADSP DHEELAKSSP DDRLDQALKE LRDAVADEVL ENLLQ

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.0
Match:	1yg2A
Description:	Structure of the Vibrio cholerae virulence activator AphA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.683379929086364	bayes_pls_golite062009
transcription regulator activity	0.16959343932447	bayes_pls_golite062009
nucleic acid binding	0.0949481158963694	bayes_pls_golite062009
DNA binding	0.00746597740509714	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [166-304]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSPSRFEVIV LDVLHRLGYG GHRDDLQRVG GTGDGGIDGV ISLDKLGLEK VYVQAKRWQN  60
   61 TVGRPELQAF YGALAGQKAK RGVFITTSGF TSQARDFAQS VEGMVLVDGE RLVHLMIENE 120
  121 VGVSSRLLKV PKLDMDYFE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.09691
Match:	1y88A
Description:	Hypothetical protein AF1548
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.286388432783973	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: