YRC Public Data Repository - Protein Structure Prediction

Protein:	MODE_ECOLI
Organism:	Escherichia coli
Length:	262 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MODE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|229127805, gi... - gi\|229127805\|ref\|ZP_04256791.1\| Transcriptional regulator, LysR [Bacillus cereus BDRD-Cer4], gi\|2286... gi\|30020498, gi\|... - gi\|30020498\|ref\|NP_832129.1\| LysR family transcriptional regulator [Bacillus cereus ATCC 14579], gi\|...	145.0	[0..14]	[244..1]
gi\|228901018, gi... - gi\|228901018\|ref\|ZP_04065229.1\| Transcriptional regulator, LysR [Bacillus thuringiensis IBL 4222], g... gi\|218541706, gi... - gi\|218897372\|ref\|YP_002445783.1\| transcriptional regulator, LysR family [Bacillus cereus G9842], gi\|... gi\|228965395, gi... - gi\|228965395\|ref\|ZP_04126485.1\| Transcriptional regulator, LysR [Bacillus thuringiensis serovar sott... gi\|74491626, gi\|... - gi\|75760891\|ref\|ZP_00740903.1\| Transcriptional regulators, LysR family [Bacillus thuringiensis serov...	143.0	[0..14]	[244..1]
gi\|89209186, gi\|... - gi\|89209186\|ref\|ZP_01187638.1\| regulatory protein, LysR:LysR, substrate-binding [Bacillus weihenstep...	142.0	[0..17]	[237..9]
gi\|49329257, gi\|... - gi\|49477701\|ref\|YP_036558.1\| LysR family transcriptional regulator [Bacillus thuringiensis serovar k...	142.0	[0..14]	[237..1]
gi\|227003114, gi... - gi\|227814751\|ref\|YP_002814760.1\| transcriptional regulator, LysR family [Bacillus anthracis str. CDC... gi\|190563361, gi... - gi\|190565334\|ref\|ZP_03018254.1\| transcriptional regulator, LysR family [Bacillus anthracis Tsiankovs... gi\|177649258, gi... - gi\|177649258\|ref\|ZP_02932260.1\| transcriptional regulator, LysR family [Bacillus anthracis str. A017... gi\|170130499, gi... - gi\|170704698\|ref\|ZP_02895164.1\| transcriptional regulator, LysR family [Bacillus anthracis str. A038... gi\|170686946, gi... - gi\|170686946\|ref\|ZP_02878165.1\| transcriptional regulator, LysR family [Bacillus anthracis str. A046... gi\|254751779 - gi\|254751779\|ref\|ZP_05203816.1\| transcriptional regulator, LysR family protein [Bacillus anthracis s... gi\|167641359, gi... - gi\|167641359\|ref\|ZP_02399610.1\| transcriptional regulator, LysR family [Bacillus anthracis str. A019... gi\|254722422 - gi\|254722422\|ref\|ZP_05184210.1\| transcriptional regulator, LysR family protein [Bacillus anthracis s... gi\|164715016, gi... - gi\|165868290\|ref\|ZP_02212950.1\| transcriptional regulator, LysR family [Bacillus anthracis str. A048... gi\|254685016 - gi\|254685016\|ref\|ZP_05148876.1\| transcriptional regulator, LysR family protein [Bacillus anthracis s... gi\|229269099, gi... - gi\|229604691\|ref\|YP_002866766.1\| transcriptional regulator, LysR family [Bacillus anthracis str. A02... gi\|254760297 - gi\|254760297\|ref\|ZP_05212321.1\| transcriptional regulator, LysR family protein [Bacillus anthracis s... gi\|49179207, gi\|... - gi\|49185280\|ref\|YP_028532.1\| LysR family transcriptional regulator [Bacillus anthracis str. Sterne],... gi\|47527731, gi\|... - gi\|47527731\|ref\|YP_019080.1\| LysR family transcriptional regulator [Bacillus anthracis str. 'Ames An... gi\|30262438, gi\|... - gi\|30262438\|ref\|NP_844815.1\| LysR family transcriptional regulator [Bacillus anthracis str. Ames], g...	141.0	[0..14]	[237..1]
gi\|47570132, gi\|... - gi\|47570132\|ref\|ZP_00240789.1\| transcription regulator LysR family VC1617, putative [Bacillus cereus...	141.0	[0..14]	[237..1]
gi\|37199931, gi\|... - gi\|37681180\|ref\|NP_935789.1\| DNA-binding transcriptional regulator OxyR [Vibrio vulnificus YJ016], g...	141.0	[0..15]	[256..1]
gi\|52143051, gi\|... - gi\|52143051\|ref\|YP_083779.1\| LysR family transcriptional regulator [Bacillus cereus E33L], gi\|519765...	140.0	[0..14]	[237..1]
gi\|254229800, gi... - gi\|75853869\|ref\|ZP_00761617.1\| COG0583: Transcriptional regulator [Vibrio sp. Ex25], gi\|254229800\|re...	139.0	[0..17]	[256..1]
gi\|27364769, gi\|... - gi\|27364769\|ref\|NP_760297.1\| DNA-binding transcriptional regulator OxyR [Vibrio vulnificus CMCP6], g...	138.0	[0..17]	[256..1]

Back

Predicted Domain #1

Region A:
Residues: [1-262]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQAEILLTLK LQQKLFADPR RISLLKHIAL SGSISQGAKD AGISYKSAWD AINEMNQLSE  60
   61 HILVERATGG KGGGGAVLTR YGQRLIQLYD LLAQIQQKAF DVLSDDDALP LNSLLAAISR 120
  121 FSLQTSARNQ WFGTITARDH DDVQQHVDVL LADGKTRLKV AITAQSGARL GLDEGKEVLI 180
  181 LLKAPWVGIT QDEAVAQNAD NQLPGIISHI ERGAEQCEVL MALPDGQTLC ATVPVNEATS 240
  241 LQQGQNVTAY FNADSVIIAT LC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.221849
Match:	1b9mA
Description:	N-terminal domain of molybdate-dependent transcriptional regulator ModE; C-terminal domain of molybdate-dependent transcriptional regulator ModE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
molybdenum ion binding	2.306486700841	bayes_pls_golite062009
transcription regulator activity	1.3574186068153	bayes_pls_golite062009
nucleic acid binding	1.03033432349652	bayes_pls_golite062009
DNA binding	0.926753986189559	bayes_pls_golite062009
binding	0.731921702708422	bayes_pls_golite062009
transcription factor activity	0.638085164477305	bayes_pls_golite062009
transcription activator activity	0.53294679084865	bayes_pls_golite062009
sequence-specific DNA binding	0.53285802828572	bayes_pls_golite062009
transcription repressor activity	0.513853050429619	bayes_pls_golite062009
transporter activity	0.437297481147526	bayes_pls_golite062009
protein binding	0.035220363090062	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: