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View Structure Prediction Details

Protein: KRR1
Organism: Homo sapiens
Length: 381 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KRR1.

Description E-value Query
Range
Subject
Range
gi|123993753, gi... - gi|124000011|gb|ABM87514.1| KRR1, small subunit (SSU) processome component, homolog (yeast) [synthet...
gi|16877011 - gi|16877011|gb|AAH16778.1| KRR1, small subunit (SSU) processome component, homolog (yeast) [Homo sap...
0.0 [1..374] [1..374]
gi|109097817 - gi|109097817|ref|XP_001117587.1| PREDICTED: HIV-1 rev binding protein 2 [Macaca mulatta]
0.0 [1..374] [1..374]
gi|73977410 - gi|73977410|ref|XP_851876.1| PREDICTED: similar to HIV-1 Rev binding protein 2 (Rev interacting prot...
0.0 [1..374] [1..374]
KRR1_BOVIN - KRR1 small subunit processome component homolog OS=Bos taurus GN=KRR1 PE=2 SV=1
0.0 [1..374] [1..376]
KRR1_MOUSE - KRR1 small subunit processome component homolog OS=Mus musculus GN=Krr1 PE=2 SV=1
0.0 [4..381] [3..380]
gi|56785318, gi|... - gi|56785318|dbj|BAD82278.1| rev protein (42.9 kD)-like [Oryza sativa Japonica Group], gi|125571797|g...
0.0 [2..380] [7..413]

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Predicted Domain #1
Region A:
Residues: [1-73]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASPSLERPE KGAGKSEFRN QKPKPENQDE SELLTVPDGW KEPAFSKEDN PRGLLEESSF  60
   61 ATLFPKYREA YLK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [74-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ECWPLVQKAL NEHHVNATLD LIEGSMTVCT TKKTFDPYII IRARDLIKLL ARSVSFEQAV  60
   61 RILQDDVACD IIKIGSLVRN KERFVKRRQR LIGPKGSTLK ALELLTNCYI MVQGNTVSAI 120
  121 GPFSGLKEVR KVVLDTMKNI HPIYNIKSLM IKRELAKDSE LR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.39794
Match: 1tuaA
Description: Structural genomics, 1.5A crystal structure of a hypothetical protein APE0754 from Aeropyrum pernix
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.07437653952404 bayes_pls_golite062009
mRNA binding 4.07599584461947 bayes_pls_golite062009
nucleic acid binding 3.68444148122352 bayes_pls_golite062009
binding 2.8667878224392 bayes_pls_golite062009
1.56143840583911 bayes_pls_golite062009
transcription regulator activity 1.43703138180882 bayes_pls_golite062009
DNA binding 1.20852534725468 bayes_pls_golite062009
protein binding 0.934192915895039 bayes_pls_golite062009
poly-pyrimidine tract binding 0.9296581376632 bayes_pls_golite062009
transcription factor activity 0.386248501195543 bayes_pls_golite062009
single-stranded RNA binding 0.3686746342524 bayes_pls_golite062009
structure-specific DNA binding 0.32222928997178 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
single-stranded DNA binding 0.1069917291606 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [236-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQSWERFLPQ FKHKNVNKRK EPKKKTVKKE YTPFPPPQPE SQIDKELASG EYFLKANQKK  60
   61 RQKMEAIKAK QAEAISKRQE ERNKAFIPPK EKPIVKPKEA STETKIDVAS IKEKVKKAKN 120
  121 KKLGALTAEE IALKMEADEK KKKKKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle