YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|151943482
Organism:	Saccharomyces cerevisiae YJM789
Length:	290 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|151943482.

Description	E-value	Query Range	Subject Range
gi\|207344981 - gi\|207344981\|gb\|EDZ71947.1\| YGR205Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|151943482 - gi\|151943482\|gb\|EDN61793.1\| conserved protein [Saccharomyces cerevisiae YJM789] TDA10_YEAST - Probable ATP-dependent kinase TDA10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TDA1... gi\|190406785 - gi\|190406785\|gb\|EDV10052.1\| kinase [Saccharomyces cerevisiae RM11-1a] TDA10 - ATP-binding protein of unknown function; crystal structure resembles that of E.coli pantothenate kin...	9.0E-69	[1..290]	[1..290]
COAA_RHIME - Pantothenate kinase OS=Rhizobium meliloti GN=coaA PE=3 SV=1 COAA_RHIME - Pantothenate kinase OS=Rhizobium meliloti (strain 1021) GN=coaA PE=3 SV=1	3.0E-55	[3..289]	[62..331]
gi\|16226442 - gi\|16226442\|gb\|AAL16169.1\|AF428401_1 At1g80380/F5I6_13 [Arabidopsis thaliana]	4.0E-55	[13..280]	[176..451]
COAA_BRUSU - Pantothenate kinase OS=Brucella suis GN=coaA PE=3 SV=1 COAA_BRUME - Pantothenate kinase OS=Brucella melitensis GN=coaA PE=3 SV=1 COAA_BRUO2 - Pantothenate kinase OS=Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512) GN=coaA PE=3 SV=1 gi\|225626468, gi... - gi\|225626468\|ref\|ZP_03784507.1\| pantothenate kinase [Brucella ceti str. Cudo], gi\|225618125\|gb\|EEH15... COAA_BRUMB - Pantothenate kinase OS=Brucella melitensis biotype 2 (strain ATCC 23457) GN=coaA PE=3 SV=1 COAA_BRUSU - Pantothenate kinase OS=Brucella suis biovar 1 (strain 1330) GN=coaA PE=3 SV=1 COAA_BRUME - Pantothenate kinase OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) GN=coaA ... gi\|254713508 - gi\|254713508\|ref\|ZP_05175319.1\| pantothenate kinase [Brucella ceti M644/93/1] gi\|254716136 - gi\|254716136\|ref\|ZP_05177947.1\| pantothenate kinase [Brucella ceti M13/05/1] gi\|254700719 - gi\|254700719\|ref\|ZP_05162547.1\| pantothenate kinase [Brucella suis bv. 5 str. 513] gi\|254705091 - gi\|254705091\|ref\|ZP_05166919.1\| pantothenate kinase [Brucella suis bv. 3 str. 686] gi\|254718151 - gi\|254718151\|ref\|ZP_05179962.1\| pantothenate kinase [Brucella sp. 83/13] COAA_BRUSI - Pantothenate kinase OS=Brucella suis (strain ATCC 23445 / NCTC 10510) GN=coaA PE=3 SV=1 COAA_BRUC2 - Pantothenate kinase OS=Brucella canis (strain ATCC 23365 / NCTC 10854) GN=coaA PE=3 SV=1	1.0E-54	[3..289]	[53..322]
COAA_RHILO - Pantothenate kinase OS=Rhizobium loti GN=coaA PE=3 SV=1 COAA_RHILO - Pantothenate kinase OS=Rhizobium loti (strain MAFF303099) GN=coaA PE=3 SV=1	2.0E-54	[3..289]	[50..319]
gi\|229706564, gi... - gi\|229836496\|ref\|ZP_04456663.1\| pantothenate kinase [Yersinia pestis Pestoides A], gi\|229706564\|gb\|E... COAA_YERPS - Pantothenate kinase OS=Yersinia pseudotuberculosis GN=coaA PE=3 SV=1 gi\|229695807, gi... - gi\|229839441\|ref\|ZP_04459600.1\| pantothenate kinase [Yersinia pestis biovar Orientalis str. PEXU2], ... gi\|229686948, gi... - gi\|229900004\|ref\|ZP_04515142.1\| pantothenate kinase [Yersinia pestis biovar Orientalis str. India 19... gi\|149289316, gi... - gi\|153997208\|ref\|ZP_02022315.1\| pantothenate kinase [Yersinia pestis CA88-4125], gi\|149289316\|gb\|EDM... COAA_YERPP - Pantothenate kinase OS=Yersinia pestis (strain Pestoides F) GN=coaA PE=3 SV=1 COAA_YERPE - Pantothenate kinase OS=Yersinia pestis GN=coaA PE=3 SV=1 COAA_YERPG - Pantothenate kinase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=coaA PE=3 SV=1 COAA_YERP3 - Pantothenate kinase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=coaA PE=3 SV=1 COAA_YERPA - Pantothenate kinase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=coaA PE=3 SV=1 COAA_YERPN - Pantothenate kinase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=coaA PE=3 SV=1 COAA_YERPB - Pantothenate kinase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=coaA PE=3 SV=1 gi\|165912058, gi... - gi\|89102990\|ref\|ZP_01175588.1\| COG1072: Panthothenate kinase [Yersinia pestis biovar Orientalis str.... gi\|165988950, gi... - gi\|166012149\|ref\|ZP_02233047.1\| pantothenate kinase [Yersinia pestis biovar Antiqua str. E1979001], ... gi\|165926264, gi... - gi\|165926264\|ref\|ZP_02222096.1\| pantothenate kinase [Yersinia pestis biovar Orientalis str. F1991016... gi\|167399681, gi... - gi\|167399681\|ref\|ZP_02305205.1\| pantothenate kinase [Yersinia pestis biovar Antiqua str. UG05-0454],... gi\|166204188, gi... - gi\|166214625\|ref\|ZP_02240660.1\| pantothenate kinase [Yersinia pestis biovar Antiqua str. B42003004],... gi\|45437908, gi\|... - gi\|45443041\|ref\|NP_994580.1\| pantothenate kinase [Yersinia pestis biovar Microtus str. 91001], gi\|45... gi\|167054182, gi... - gi\|167426800\|ref\|ZP_02318553.1\| pantothenate kinase [Yersinia pestis biovar Mediaevalis str. K197300... gi\|22124388, gi\|... - gi\|22124388\|ref\|NP_667811.1\| pantothenate kinase [Yersinia pestis KIM], gi\|21957169\|gb\|AAM84062.1\|AE... gi\|167422996, gi... - gi\|167422996\|ref\|ZP_02314749.1\| pantothenate kinase [Yersinia pestis biovar Orientalis str. MG05-102... gi\|15981674, gi\|... - gi\|218930763\|ref\|YP_002348638.1\| pantothenate kinase [Yersinia pestis CO92], gi\|16123895\|ref\|NP_4072... COAA_YERPY - Pantothenate kinase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=coaA PE=3 SV=1 COAA_YERPS - Pantothenate kinase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=coaA PE=3 SV=1 gi\|167470585 - gi\|167470585\|ref\|ZP_02335289.1\| pantothenate kinase [Yersinia pestis FV-1]	4.0E-54	[3..288]	[49..316]
COAA_SALPB - Pantothenate kinase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=coaA PE=3 SV=1 COAA_SALTY - Pantothenate kinase OS=Salmonella typhimurium GN=coaA PE=3 SV=1 COAA_SALTY - Pantothenate kinase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=coaA PE=3 SV=... COAA_SALPC - Pantothenate kinase OS=Salmonella paratyphi C (strain RKS4594) GN=coaA PE=3 SV=1 COAA_SALTY - Pantothenate kinase OS=Salmonella typhimurium GN=coaA PE=3 SV=1 gi\|205321453, gi... - gi\|205357489\|ref\|ZP_02348072.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Sai... gi\|205326991, gi... - gi\|205358199\|ref\|ZP_02576422.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar 4,[... gi\|205335977, gi... - gi\|205359466\|ref\|ZP_02670230.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Hei... COAA_SALEP - Pantothenate kinase OS=Salmonella enteritidis PT4 (strain P125109) GN=coaA PE=3 SV=1 COAA_SALHS - Pantothenate kinase OS=Salmonella heidelberg (strain SL476) GN=coaA PE=3 SV=1 lcl\|NC_016856.1_... - [gene=coaA] [protein=pantothenate kinase] [protein_id=YP_005240422.1] [location=complement(4372275..... gi\|194458277, gi... - gi\|194471913\|ref\|ZP_03077897.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Ken... COAA_SALDC - Pantothenate kinase OS=Salmonella dublin (strain CT_02021853) GN=coaA PE=3 SV=1 gi\|200388743, gi... - gi\|200388743\|ref\|ZP_03215355.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Vir... COAA_SALCH - Pantothenate kinase OS=Salmonella choleraesuis (strain SC-B67) GN=coaA PE=3 SV=2 COAA_SALPB - Pantothenate kinase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=coaA PE=3 SV=1 COAA_SALCH - Pantothenate kinase OS=Salmonella choleraesuis GN=coaA PE=3 SV=2 gi\|205340453, gi... - gi\|205340453\|gb\|EDZ27217.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Weltevr... COAA_SALCH - Pantothenate kinase OS=Salmonella choleraesuis GN=coaA PE=3 SV=2	5.0E-54	[3..288]	[49..316]
COAA_SALTI - Pantothenate kinase OS=Salmonella typhi GN=coaA PE=3 SV=1 gi\|213999715 - gi\|213999715\|ref\|ZP_03410450.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typ... COAA_SALA4 - Pantothenate kinase OS=Salmonella agona (strain SL483) GN=coaA PE=3 SV=1 COAA_SALPK - Pantothenate kinase OS=Salmonella paratyphi A (strain AKU_12601) GN=coaA PE=3 SV=1 gi\|205360640, gi... - gi\|205360640\|ref\|ZP_02684926.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Had... gi\|213163738 - gi\|213163738\|ref\|ZP_03349448.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typ... gi\|168468124, gi... - gi\|195628796\|gb\|EDX48226.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Newport... COAA_SALPA - Pantothenate kinase OS=Salmonella paratyphi A GN=coaA PE=3 SV=1 COAA_SALNS - Pantothenate kinase OS=Salmonella newport (strain SL254) GN=coaA PE=3 SV=1 COAA_SALSV - Pantothenate kinase OS=Salmonella schwarzengrund (strain CVM19633) GN=coaA PE=3 SV=1 gi\|16762309 - gi\|16762309\|ref\|NP_457926.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typhi ... COAA_SALTI - Pantothenate kinase OS=Salmonella typhi GN=coaA PE=3 SV=1 COAA_SALPA - Pantothenate kinase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=coaA PE=3 SV=1 gi\|29139432, gi\|... - gi\|29143797\|ref\|NP_807139.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typhi ...	9.0E-54	[3..288]	[49..316]
gi\|121546650, gi... - gi\|121591499\|ref\|ZP_01678768.1\| pantothenate kinase [Vibrio cholerae 2740-80], gi\|121546650\|gb\|EAX56... gi\|11355762 - gi\|11355762\|pir\|\|F82337 pantothenate kinase VC0320 [imported] - Vibrio cholerae (strain N16961 sero... gi\|124117414, gi... - gi\|153224981\|ref\|ZP_01954663.1\| pantothenate kinase [Vibrio cholerae MAK 757], gi\|124117414\|gb\|EAY36... gi\|254286214, gi... - gi\|254286214\|ref\|ZP_04961173.1\| pantothenate kinase [Vibrio cholerae AM-19226], gi\|197752204\|ref\|YP_... gi\|121730117, gi... - gi\|121730117\|ref\|ZP_01682517.1\| pantothenate kinase [Vibrio cholerae V52], gi\|121628138\|gb\|EAX60671.... gi\|227116726, gi... - gi\|227116726\|ref\|YP_002818622.1\| pantothenate kinase [Vibrio cholerae O395], gi\|227012176\|gb\|ACP0838... gi\|254227121, gi... - gi\|254227121\|ref\|ZP_04920671.1\| pantothenate kinase [Vibrio cholerae V51], gi\|225354216\|ref\|YP_00272... gi\|125618896, gi... - gi\|254851629\|ref\|ZP_05240979.1\| pantothenate kinase [Vibrio cholerae MO10], gi\|254847334\|gb\|EET25748... gi\|126518627, gi... - gi\|153823850\|ref\|ZP_01976517.1\| pantothenate kinase [Vibrio cholerae B33], gi\|126518627\|gb\|EAZ75850.... gi\|153820077, gi... - gi\|153820077\|ref\|ZP_01972744.1\| pantothenate kinase [Vibrio cholerae NCTC 8457], gi\|126509377\|gb\|EAZ... gi\|15640347, gi\|... - gi\|9654733\|gb\|AAF93493.1\| pantothenate kinase [Vibrio cholerae O1 biovar El Tor str. N16961], gi\|156... gi\|227080532, gi... - gi\|227080532\|ref\|YP_002809083.1\| pantothenate kinase [Vibrio cholerae M66-2], gi\|227008420\|gb\|ACP046...	3.0E-53	[4..288]	[110..375]

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Predicted Domain #1

Region A:
Residues: [1-290]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCDKSKTVLD YTIEFLDKYI PEWFETGNKC PLFIFFSGPQ GSGKSFTSIQ IYNHLMEKYG  60
   61 GEKSIGYASI DDFYLTHEDQ LKLNEQFKNN KLLQGRGLPG THDMKLLQEV LNTIFNNNEH 120
  121 PDQDTVVLPK YDKSQFKGEG DRCPTGQKIK LPVDIFILEG WFLGFNPILQ GIENNDLLTG 180
  181 DMVDVNAKLF FYSDLLWRNP EIKSLGIVFT TDNINNVYGW RLQQEHELIS KVGKGMTDEQ 240
  241 VHAFVDRYMP SYKLYLNDFV RSESLGSIAT LTLGIDSNRN VYSTKTRCIE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.69897
Match:	1esmA_
Description:	Pantothenate kinase PanK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.26687146372087	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.420384345567397	bayes_pls_golite062009
pyrophosphatase activity	0.411077559082206	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.399864241228259	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.398496265411009	bayes_pls_golite062009
catalytic activity	0.234613562021476	bayes_pls_golite062009
hydrolase activity	0.216831145240405	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: