YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|148874455, gi...
Organism:	Vibrio cholerae 623-39
Length:	210 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|148874455, gi....

Description	E-value	Query Range	Subject Range
gi\|119944168, gi... - gi\|119944168\|ref\|YP_941848.1\| cAMP-regulatory protein [Psychromonas ingrahamii 37], gi\|119862772\|gb\|...	168.0	[0..8]	[210..8]
gi\|2190360 - gi\|2190360\|emb\|CAA61609.1\| CRP regulatory protein [Erwinia chrysanthemi]	167.0	[0..8]	[210..8]
gi\|90311619, gi\|... - gi\|90407336\|ref\|ZP_01215522.1\| cAMP-regulatory protein [Psychromonas sp. CNPT3], gi\|90311619\|gb\|EAS3...	167.0	[0..8]	[210..8]
gi\|2580527 - gi\|2580527\|gb\|AAC45784.1\| cyclic AMP receptor protein [Vibrio cholerae] gi\|227119052, gi... - gi\|75827864\|ref\|ZP_00757299.1\| COG0664: cAMP-binding proteins - catabolite gene activator and regula...	166.0	[0..8]	[210..8]
gi\|90580842, gi\|... - gi\|90580842\|ref\|ZP_01236644.1\| putative cyclic AMP receptor protein [Vibrio angustum S14], gi\|904379... gi\|89075223, gi\|... - gi\|89075223\|ref\|ZP_01161654.1\| putative cyclic AMP receptor protein [Photobacterium sp. SKA34], gi\|8...	166.0	[0..8]	[210..8]
gi\|90325352, gi\|... - gi\|90413579\|ref\|ZP_01221569.1\| putative cyclic AMP receptor protein [Photobacterium profundum 3TCK],... gi\|54307514, gi\|... - gi\|54307514\|ref\|YP_128534.1\| cAMP-regulatory protein [Photobacterium profundum SS9], gi\|46911934\|emb...	166.0	[0..8]	[210..8]
CRP_ENTAE - cAMP-activated global transcriptional regulator CRP OS=Enterobacter aerogenes GN=crp PE=1 SV=1 lcl\|NC_016856.1_... - [gene=crp] [protein=cAMP-regulatory protein] [protein_id=YP_005239659.1] [location=3629504..3630136] gi\|62181970, gi\|... - gi\|62181970\|ref\|YP_218387.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serovar Ch... gi\|348346 - gi\|348346\|pir\|\|A44903 cAMP receptor protein - Klebsiella pneumoniae CRP_KLEAE - Catabolite gene activator OS=Klebsiella aerogenes GN=crp PE=4 SV=1 gi\|46811323 - gi\|46811323\|gb\|AAT01930.1\| cAMP receptor protein [Salmonella enterica subsp. enterica serovar Abortu... CRP_SALTY - cAMP-activated global transcriptional regulator CRP OS=Salmonella typhimurium (strain LT2 / SGSC1412... gi\|194448344, gi... - gi\|194448344\|ref\|YP_002047489.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serova... gi\|194446186, gi... - gi\|194446186\|ref\|YP_002042717.1\| catabolite gene activator [Salmonella enterica subsp. enterica sero... gi\|205344366, gi... - gi\|205344366\|gb\|EDZ31130.1\| catabolite gene activator [Salmonella enterica subsp. enterica serovar W... gi\|195632099, gi... - gi\|195632099\|gb\|EDX50583.1\| catabolite gene activator [Salmonella enterica subsp. enterica serovar N... gi\|197241683, gi... - gi\|197263428\|ref\|ZP_03163502.1\| catabolite gene activator [Salmonella enterica subsp. enterica serov... gi\|197214290, gi... - gi\|197250587\|ref\|YP_002148385.1\| catabolite gene activator [Salmonella enterica subsp. enterica sero... gi\|194735165, gi... - gi\|194735165\|ref\|YP_002116409.1\| catabolite gene activator [Salmonella enterica subsp. enterica sero... gi\|194458985, gi... - gi\|194472621\|ref\|ZP_03078605.1\| catabolite gene activator [Salmonella enterica subsp. enterica serov... gi\|167994566, gi... - gi\|205327575\|gb\|EDZ14339.1\| catabolite gene activator [Salmonella enterica subsp. enterica serovar 4... gi\|205325761, gi... - gi\|205325761\|gb\|EDZ13600.1\| catabolite gene activator [Salmonella enterica subsp. enterica serovar S... gi\|161616497, gi... - gi\|161616497\|ref\|YP_001590462.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serova... gi\|160867315, gi... - gi\|161505968\|ref\|YP_001573080.1\| cAMP-regulatory protein [Salmonella enterica subsp. arizonae serova... gi\|168260819, gi... - gi\|205350240\|gb\|EDZ36871.1\| catabolite gene activator [Salmonella enterica subsp. enterica serovar H... gi\|205338686, gi... - gi\|205338686\|gb\|EDZ25450.1\| catabolite gene activator [Salmonella enterica subsp. enterica serovar H... CRP_SALTY - Catabolite gene activator OS=Salmonella typhimurium GN=crp PE=4 SV=1 gi\|197291524, gi... - gi\|197291524\|gb\|EDY30876.1\| catabolite gene activator [Salmonella enterica subsp. enterica serovar S... gi\|205333074, gi... - gi\|205333074\|gb\|EDZ19838.1\| catabolite gene activator [Salmonella enterica subsp. enterica serovar K... gi\|228557955, gi... - gi\|228557955\|gb\|EEK22620.1\| hypothetical protein CIT292_00449 [Citrobacter youngae ATCC 29220], gi\|2... gi\|157086144, gi... - gi\|157148939\|ref\|YP_001456258.1\| cAMP-regulatory protein [Citrobacter koseri ATCC BAA-895], gi\|15708... gi\|152972251, gi... - gi\|152972251\|ref\|YP_001337397.1\| cAMP-regulatory protein [Klebsiella pneumoniae subsp. pneumoniae MG... gi\|238896840, gi... - gi\|238896840\|ref\|YP_002921585.1\| catabolite activator protein [Klebsiella pneumoniae NTUH-K2044], gi... gi\|237728681, gi... - gi\|237728681\|ref\|ZP_04559162.1\| catabolite gene activator protein [Citrobacter sp. 30_2], gi\|2269093... CRP_SALTY - Catabolite gene activator OS=Salmonella typhimurium GN=crp PE=4 SV=1 gi\|238921513, gi... - gi\|238921513\|ref\|YP_002935028.1\| hypothetical protein NT01EI_3665 [Edwardsiella ictaluri 93-146], gi... gi\|238913590 - gi\|238913590\|ref\|ZP_04657427.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serovar... gi\|206578857, gi... - gi\|206578857\|ref\|YP_002236256.1\| catabolite gene activator [Klebsiella pneumoniae 342], gi\|206567915... gi\|204928836, gi... - gi\|204928836\|ref\|ZP_03220035.1\| catabolite gene activator [Salmonella enterica subsp. enterica serov... gi\|199604370, gi... - gi\|200387272\|ref\|ZP_03213884.1\| catabolite gene activator [Salmonella enterica subsp. enterica serov... gi\|197940226, gi... - gi\|198245710\|ref\|YP_002217427.1\| catabolite gene activator [Salmonella enterica subsp. enterica sero... gi\|283787994\|ref... - cyclic AMP receptor protein (catabolite gene activator) [Citrobacter rodentium ICC168] gi\|224585260, gi... - gi\|224585260\|ref\|YP_002639059.1\| cyclic AMP receptor protein,catabolite gene activator [Salmonella e... gi\|209905850, gi... - gi\|209905850\|ref\|ZP_03280334.1\| hypothetical protein ENTCAN_00075 [Enterobacter cancerogenus ATCC 35... gi\|207858707, gi... - gi\|207858707\|ref\|YP_002245358.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serova...	166.0	[0..8]	[210..8]
gi\|227343661, gi... - gi\|227343661\|pdb\|2WC2\|B Chain B, Nmr Structure Of Catabolite Activator Protein In The Unliganded Sta... gi\|93278608, gi\|... - gi\|93278614\|pdb\|1ZRF\|B Chain B, 4 Crystal Structures Of Cap-Dna With All Base-Pair Substitutions At ...	166.0	[0..8]	[210..7]
gi\|18032026 - gi\|18032026\|gb\|AAL51151.1\| cyclic AMP receptor protein [Yersinia enterocolitica] gi\|238788937, gi... - gi\|77975018\|ref\|ZP_00830555.1\| COG0664: cAMP-binding proteins - catabolite gene activator and regula... gi\|123444130, gi... - gi\|123444130\|ref\|YP_001008100.1\| cAMP-regulatory protein [Yersinia enterocolitica subsp. enterocolit... gi\|25300724 - pir\|\|AC0022 cAMP-regulatory protein crp [imported] - Yersinia pestis (strain CO92) gi\|238715936, gi... - gi\|77958268\|ref\|ZP_00822304.1\| COG0664: cAMP-binding proteins - catabolite gene activator and regula... gi\|45440035, gi\|... - gi\|45440035\|ref\|NP_991574.1\| cAMP-regulatory protein [Yersinia pestis biovar Microtus str. 91001], g... gi\|22127826, gi\|... - gi\|22127826\|ref\|NP_671249.1\| cAMP-regulatory protein [Yersinia pestis KIM], gi\|21960959\|gb\|AAM87500.... gi\|15978278, gi\|... - gi\|218927384\|ref\|YP_002345259.1\| cAMP-regulatory protein [Yersinia pestis CO92], gi\|16120516\|ref\|NP_... gi\|51598019, gi\|... - gi\|51598019\|ref\|YP_072210.1\| cAMP-regulatory protein [Yersinia pseudotuberculosis IP 32953], gi\|5159... gi\|77634615, gi\|... - gi\|77634615\|ref\|ZP_00796712.1\| COG0664: cAMP-binding proteins - catabolite gene activator and regula... gi\|238698058, gi... - gi\|238763756\|ref\|ZP_04624715.1\| hypothetical protein ykris0001_23360 [Yersinia kristensenii ATCC 336... gi\|152960162, gi... - gi\|77631153\|ref\|ZP_00793739.1\| COG0664: cAMP-binding proteins - catabolite gene activator and regula... gi\|238758738, gi... - gi\|238758738\|ref\|ZP_04619912.1\| hypothetical protein yaldo0001_31510 [Yersinia aldovae ATCC 35236], ... Q664P0\|Q664P0_YERPS - CAMP-regulatory protein - Yersinia pseudotuberculosis gi\|238751109, gi... - gi\|238751109\|ref\|ZP_04612604.1\| hypothetical protein yrohd0001_12920 [Yersinia rohdei ATCC 43380], g... gi\|229842114, gi... - gi\|229842114\|ref\|ZP_04462269.1\| cyclic AMP receptor protein [Yersinia pestis biovar Orientalis str. ... gi\|229696398, gi... - gi\|229840032\|ref\|ZP_04460191.1\| cyclic AMP receptor protein [Yersinia pestis biovar Orientalis str. ... gi\|229706412, gi... - gi\|229836344\|ref\|ZP_04456511.1\| cyclic AMP receptor protein [Yersinia pestis Pestoides A], gi\|229706... gi\|165920175, gi... - gi\|165927899\|ref\|ZP_02223731.1\| catabolite gene activator [Yersinia pestis biovar Orientalis str. F1... gi\|165990489, gi... - gi\|166010399\|ref\|ZP_02231297.1\| catabolite gene activator [Yersinia pestis biovar Antiqua str. E1979... gi\|166205444, gi... - gi\|166213146\|ref\|ZP_02239181.1\| catabolite gene activator [Yersinia pestis biovar Antiqua str. B4200... gi\|167051444, gi... - gi\|167398940\|ref\|ZP_02304464.1\| catabolite gene activator [Yersinia pestis biovar Antiqua str. UG05-... gi\|167419214, gi... - gi\|167419214\|ref\|ZP_02310967.1\| catabolite gene activator [Yersinia pestis biovar Orientalis str. MG... gi\|165940015, gi... - gi\|89102998\|ref\|ZP_01175596.1\| COG0664: cAMP-binding proteins - catabolite gene activator and regula... gi\|108809288, gi... - gi\|108809288\|ref\|YP_653204.1\| cAMP-regulatory protein [Yersinia pestis Antiqua], gi\|108781201\|gb\|ABG... gi\|229904586, gi... - gi\|229904586\|ref\|ZP_04519697.1\| cyclic AMP receptor protein [Yersinia pestis Nepal516], gi\|229678704... gi\|149290182, gi... - gi\|150260774\|ref\|ZP_01917502.1\| cAMP-regulatory protein [Yersinia pestis CA88-4125], gi\|149290182\|gb... gi\|167425691, gi... - gi\|167425691\|ref\|ZP_02317444.1\| catabolite gene activator [Yersinia pestis biovar Mediaevalis str. K... gi\|170022509, gi... - gi\|170022509\|ref\|YP_001719014.1\| cAMP-regulatory protein [Yersinia pseudotuberculosis YPIII], gi\|169... gi\|186897215, gi... - gi\|186897215\|ref\|YP_001874327.1\| cAMP-regulatory protein [Yersinia pseudotuberculosis PB1/+], gi\|186... gi\|145597421, gi... - gi\|145597421\|ref\|YP_001161496.1\| cAMP-regulatory protein [Yersinia pestis Pestoides F], gi\|145209117...	166.0	[0..8]	[210..8]
gi\|29144305, gi\|... - gi\|29144305\|ref\|NP_807647.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serovar Ty... gi\|16762818 - gi\|16762818\|ref\|NP_458435.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serovar Ty... gi\|214000203 - gi\|214000203\|ref\|ZP_03410938.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serovar... gi\|213649013 - gi\|213649013\|ref\|ZP_03379066.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serovar... gi\|213584095 - gi\|213584095\|ref\|ZP_03365921.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serovar... gi\|213426762 - gi\|213426762\|ref\|ZP_03359512.1\| cAMP-regulatory protein [Salmonella enterica subsp. enterica serovar... gi\|25300728, gi\|... - gi\|25300728\|pir\|\|AG1002 cyclic AMP receptor protein,catabolite gene activator [imported] - Salmonell...	166.0	[0..8]	[210..8]

Back

Predicted Domain #1

Region A:
Residues: [1-210]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLGKPQTDP TLEWFLSHCH IHKYPSKSTL IHAGEKAETL YYIVKGSVAV LIKDEEGKEM  60
   61 ILSYLNQGDF IGELGLFEEG QERTAWVRAK TPCEVAEISF KKFRQLIQVN PDILMRLSGQ 120
  121 MARRLQVTSQ KVGDLAFLDV TGRIAQTLLN LARQPDAMTH PDGMQIKITR QEIGQIVGCS 180
  181 RETVGRILKM LEEQNLISAH GKTIVVYGTR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.39794
Match:	1i5zA
Description:	Catabolite gene activator protein (CAP), C-terminal domain; Catabolite gene activator protein, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.00625548877971	bayes_pls_golite062009
binding	0.891226539481379	bayes_pls_golite062009
nucleic acid binding	0.59306579636505	bayes_pls_golite062009
sequence-specific DNA binding	0.53285802828572	bayes_pls_golite062009
DNA binding	0.47798148720399	bayes_pls_golite062009
transcription factor activity	0.159026311884013	bayes_pls_golite062009
protein binding	0.094542444184087	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: