YRC Public Data Repository - Protein Structure Prediction

Protein:	GABT_ECOLI
Organism:	Escherichia coli
Length:	426 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GABT_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|254686709 - gi\|254686709\|ref\|ZP_05150567.1\| 4-aminobutyrate aminotransferase [Bacillus anthracis str. CNEVA-9066... gi\|254739066 - gi\|254739066\|ref\|ZP_05196768.1\| 4-aminobutyrate aminotransferase [Bacillus anthracis str. Western No... gi\|21398270 - ref\|NP_654255.1\| aminotran_3, Aminotransferase class-III [Bacillus anthracis str. A2012] gi\|254761905 - gi\|254761905\|ref\|ZP_05213754.1\| 4-aminobutyrate aminotransferase [Bacillus anthracis str. Australia ... gi\|254742312 - gi\|254742312\|ref\|ZP_05199998.1\| 4-aminobutyrate aminotransferase [Bacillus anthracis str. Kruger B] gi\|254756088 - gi\|254756088\|ref\|ZP_05208117.1\| 4-aminobutyrate aminotransferase [Bacillus anthracis str. Vollum] gi\|49183338, gi\|... - gi\|49183338\|ref\|YP_026590.1\| 4-aminobutyrate aminotransferase [Bacillus anthracis str. Sterne], gi\|4... gi\|47500740, gi\|... - gi\|47525592\|ref\|YP_016941.1\| 4-aminobutyrate aminotransferase [Bacillus anthracis str. 'Ames Ancesto... gi\|30260495, gi\|... - gi\|30260495\|ref\|NP_842872.1\| 4-aminobutyrate aminotransferase [Bacillus anthracis str. Ames], gi\|302...	421.0	[0..3]	[422..17]
gi\|52144923, gi\|... - gi\|52144923\|ref\|YP_081906.1\| 4-aminobutyrate aminotransferase [Bacillus cereus E33L], gi\|51978392\|gb...	420.0	[0..3]	[422..17]
gi\|65317747 - gi\|65317747\|ref\|ZP_00390706.1\| COG0160: 4-aminobutyrate aminotransferase and related aminotransferas...	420.0	[0..3]	[422..21]
gi\|42735351, gi\|... - gi\|42779435\|ref\|NP_976682.1\| 4-aminobutyrate aminotransferase [Bacillus cereus ATCC 10987], gi\|42735...	420.0	[0..3]	[422..31]
gi\|47553759, gi\|... - gi\|47569576\|ref\|ZP_00240254.1\| 4-aminobutyrate aminotransferase [Bacillus cereus G9241], gi\|47553759...	419.0	[0..3]	[422..17]
gi\|116053993, gi... - gi\|32043437\|ref\|ZP_00140699.1\| COG0160: 4-aminobutyrate aminotransferase and related aminotransferas...	419.0	[0..1]	[425..1]
gi\|89157404, gi\|... - gi\|89204777\|ref\|ZP_01183353.1\| 4-aminobutyrate aminotransferase [Bacillus weihenstephanensis KBAB4],...	419.0	[0..3]	[423..17]
gi\|49328339, gi\|... - gi\|49476783\|ref\|YP_034643.1\| 4-aminobutyrate aminotransferase [Bacillus thuringiensis serovar konkuk...	418.0	[0..3]	[422..17]
gi\|150961678, gi... - gi\|94413729\|ref\|ZP_01293606.1\| hypothetical protein PaerP_01004514 [Pseudomonas aeruginosa PA7], gi\|... gi\|218889006, gi... - gi\|218889006\|ref\|YP_002437870.1\| 4-aminobutyrate aminotransferase [Pseudomonas aeruginosa LESB58], g... gi\|107099247 - gi\|107099247\|ref\|ZP_01363165.1\| hypothetical protein PaerPA_01000258 [Pseudomonas aeruginosa PACS2] gi\|254243364, gi... - gi\|84324641\|ref\|ZP_00972698.1\| COG0160: 4-aminobutyrate aminotransferase and related aminotransferas... gi\|11347316 - pir\|\|B83611 4-aminobutyrate aminotransferase PA0266 [imported] - Pseudomonas aeruginosa (strain PAO1... DAVT_PSEAE - 5-aminovalerate aminotransferase DavT OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS...	418.0	[0..1]	[425..1]
gi\|84318556, gi\|... - gi\|84318556\|ref\|ZP_00966979.1\| COG0160: 4-aminobutyrate aminotransferase and related aminotransferas...	417.0	[0..1]	[425..1]

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Predicted Domain #1

Region A:
Residues: [1-426]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSNKELMQR RSQAIPRGVG QIHPIFADRA ENCRVWDVEG REYLDFAGGI AVLNTGHLHP  60
   61 KVVAAVEAQL KKLSHTCFQV LAYEPYLELC EIMNQKVPGD FAKKTLLVTT GSEAVENAVK 120
  121 IARAATKRSG TIAFSGAYHG RTHYTLALTG KVNPYSAGMG LMPGHVYRAL YPCPLHGISE 180
  181 DDAIASIHRI FKNDAAPEDI AAIVIEPVQG EGGFYASSPA FMQRLRALCD EHGIMLIADE 240
  241 VQSGAGRTGT LFAMEQMGVA PDLTTFAKSI AGGFPLAGVT GRAEVMDAVA PGGLGGTYAG 300
  301 NPIACVAALE VLKVFEQENL LQKANDLGQK LKDGLLAIAE KHPEIGDVRG LGAMIAIELF 360
  361 EDGDHNKPDA KLTAEIVARA RDKGLILLSC GPYYNVLRIL VPLTIEDAQI RQGLEIISQC 420
  421 FDEAKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	116.0
Match:	1sf2A
Description:	Structure of E. coli gamma-aminobutyrate aminotransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-aminobutyrate transaminase activity	9.08769857759091	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase binding	8.44659094913875	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	3.359406422625	bayes_pls_golite062009
transferase activity	2.59075614411581	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
5-aminolevulinate synthase activity	1.85905571238884	bayes_pls_golite062009
adenosylmethionine-8-amino-7-oxononanoate transaminase activity	1.74778109525713	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	1.46601963907552	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	1.46601963907552	bayes_pls_golite062009
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	1.4383564662931	bayes_pls_golite062009
glutamate decarboxylase activity	1.34215658716536	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.19150094103499	bayes_pls_golite062009
transcription regulator activity	0.977210827616757	bayes_pls_golite062009
nucleic acid binding	0.892872530648552	bayes_pls_golite062009
binding	0.892049641082766	bayes_pls_golite062009
ligase activity	0.827063849687833	bayes_pls_golite062009
DNA binding	0.803965264969424	bayes_pls_golite062009
kynureninase activity	0.777830972119923	bayes_pls_golite062009
carbon-sulfur lyase activity	0.698312655247044	bayes_pls_golite062009
intramolecular transferase activity, transferring amino groups	0.659071155545801	bayes_pls_golite062009
transcription factor activity	0.597417107954964	bayes_pls_golite062009
N-succinyltransferase activity	0.52897097514616	bayes_pls_golite062009
ornithine-oxo-acid transaminase activity	0.311107335626334	bayes_pls_golite062009
N-acyltransferase activity	0.2609065149092	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009
cystathionine beta-lyase activity	0.15938456446406	bayes_pls_golite062009
hydrolase activity	0.158765164178244	bayes_pls_golite062009
amine binding	0.14702601411039	bayes_pls_golite062009
methyltransferase activity	0.103986924428507	bayes_pls_golite062009
sulfurtransferase activity	0.0450490929307473	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.0254276656964899	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: