YRC Public Data Repository - Protein Structure Prediction

Protein:	EUTR_ECOLI
Organism:	Escherichia coli
Length:	350 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EUTR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|83570660 - gi\|83570660\|ref\|ZP_00922103.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Shigella d...	224.0	[0..1]	[350..1]
gi\|75196451, gi\|... - gi\|75196451\|ref\|ZP_00706521.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	224.0	[0..1]	[350..1]
gi\|75515782, gi\|... - gi\|75515782\|ref\|ZP_00737917.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi... gi\|124498334, gi... - gi\|124531851\|ref\|ZP_01701958.1\| transcriptional regulator, AraC family [Escherichia coli B], gi\|1244... gi\|170019281, gi... - gi\|170019281\|ref\|YP_001724235.1\| transcriptional regulator EutR [Escherichia coli ATCC 8739], gi\|169...	223.0	[0..1]	[350..1]
gi\|110615926, gi... - gi\|110806378\|ref\|YP_689898.1\| transcriptional regulator EutR [Shigella flexneri 5 str. 8401], gi\|110...	223.0	[0..1]	[350..1]
gi\|218428136, gi... - gi\|218690572\|ref\|YP_002398784.1\| transcriptional regulator EutR [Escherichia coli ED1a], gi\|21842813... gi\|26109219, gi\|... - gi\|26248813\|ref\|NP_754853.1\| transcriptional regulator EutR [Escherichia coli CFT073], gi\|26109219\|g... gi\|227887482, gi... - gi\|227887482\|ref\|ZP_04005287.1\| transcriptional regulator EutR [Escherichia coli 83972], gi\|22783583...	223.0	[0..1]	[350..1]
gi\|189003430, gi... - gi\|189003430\|gb\|EDU72416.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 str. E... gi\|168773651, gi... - gi\|187770615\|gb\|EDU34459.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 str. E... gi\|237704960, gi... - gi\|237704960\|ref\|ZP_04535441.1\| transcriptional regulator EutR [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|189378594, gi... - gi\|189378594\|gb\|EDU97010.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 str. E... gi\|254794390, gi... - gi\|254794390\|ref\|YP_003079227.1\| predicted DNA-binding transcriptional regulator [Escherichia coli O... gi\|189372362, gi... - gi\|189372362\|gb\|EDU90778.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 str. E... gi\|208727673, gi... - gi\|208807872\|ref\|ZP_03250209.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 st... gi\|91073349, gi\|... - gi\|91211775\|ref\|YP_541761.1\| transcriptional regulator EutR [Escherichia coli UTI89], gi\|91073349\|gb... gi\|195936588 - gi\|195936588\|ref\|ZP_03081970.1\| transcriptional regulator EutR [Escherichia coli O157:H7 str. EC4024... gi\|15832562, gi\|... - gi\|15832562\|ref\|NP_311335.1\| transcriptional regulator EutR [Escherichia coli O157:H7 str. Sakai], g... gi\|208738690, gi... - gi\|208818567\|ref\|ZP_03258887.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 st... gi\|110344210, gi... - gi\|110642618\|ref\|YP_670348.1\| transcriptional regulator EutR [Escherichia coli 536], gi\|110344210\|gb... gi\|208734414, gi... - gi\|208813137\|ref\|ZP_03254466.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 st... gi\|189356609, gi... - gi\|189356609\|gb\|EDU75028.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 str. E... gi\|188017026, gi... - gi\|188017026\|gb\|EDU55148.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 str. E... gi\|168768528, gi... - gi\|189362252\|gb\|EDU80671.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 str. E... gi\|168761045, gi... - gi\|189368401\|gb\|EDU86817.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 str. E... gi\|117624642, gi... - gi\|117624642\|ref\|YP_853555.1\| transcriptional regulator EutR [Escherichia coli APEC O1], gi\|11551376... gi\|217327565, gi... - gi\|217327565\|ref\|ZP_03443648.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 st... gi\|209396622, gi... - gi\|209396622\|ref\|YP_002271914.1\| putative transcriptional regulator EutR [Escherichia coli O157:H7 s... gi\|218433041, gi... - gi\|218705944\|ref\|YP_002413463.1\| transcriptional regulator EutR [Escherichia coli UMN026], gi\|218433... gi\|218559382, gi... - gi\|218559382\|ref\|YP_002392295.1\| transcriptional regulator EutR [Escherichia coli S88], gi\|218366151... gi\|209764002, gi... - pir\|\|G85886 probable ARAC-type regulatory protein yfeG [imported] - Escherichia coli (strain O157:H7... gi\|12516818, gi\|... - gi\|15802968\|ref\|NP_288998.1\| transcriptional regulator EutR [Escherichia coli O157:H7 EDL933], gi\|12... gi\|15832562, gi\|... - gi\|15832562\|ref\|NP_311335.1\| putative ARAC-type regulatory protein [Escherichia coli O157:H7], gi\|13... gi\|190906809, gi... - gi\|75240095\|ref\|ZP_00724054.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	222.0	[0..1]	[350..1]
gi\|194427326, gi... - gi\|75211407\|ref\|ZP_00711497.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	222.0	[0..1]	[350..1]
gi\|209919918, gi... - gi\|209919918\|ref\|YP_002294002.1\| transcriptional regulator EutR [Escherichia coli SE11], gi\|20991317... gi\|218554969, gi... - gi\|218554969\|ref\|YP_002387882.1\| transcriptional regulator EutR [Escherichia coli IAI1], gi\|21836173... gi\|75257249, gi\|... - gi\|75257249\|ref\|ZP_00728773.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	222.0	[0..1]	[350..1]
gi\|81241979, gi\|... - gi\|82777831\|ref\|YP_404180.1\| transcriptional regulator EutR [Shigella dysenteriae Sd197], gi\|8124197...	221.0	[0..1]	[350..1]
gi\|75187190, gi\|... - gi\|75187190\|ref\|ZP_00700457.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	221.0	[0..1]	[350..1]

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Predicted Domain #1

Region A:
Residues: [1-233]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKTRTANLH HLYHEPLPEN LKLTPKVEVD NVHQRQTTDV YEHALTITAW QQIYDQLHPG  60
   61 KFHGEFTEIL LDDIQVFREY TGLALRQSCL VWPNSFWFGI PATRGEQGFI GSQCLGSAEI 120
  121 ATRPGGTEFE LSTPDDYTIL GVVLSEDVIT RQANFLHNPD RVLHMLRNQS ALEVKEQHKA 180
  181 ALWGFVQQAL ATFCENPENL HQPAVRKVLG DNLLMAMGAM LEEAQPMVTA ESI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.30103
Match:	2aacA
Description:	Regulatory protein AraC
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [234-350]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHQSYRRLLS RAREYVLENM SEPVTVLDLC NQLHVSRRTL QNAFHAILGI GPNAWLKRIR  60
   61 LNAVRRELIS PWSQSMTVKD AAMQWGFWHL GQFATDYQQL FSEKPSLTLH QRMREWG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.522879
Match:	1d5yA
Description:	Rob transcription factor, N-terminal domain; Rob transcription factor, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.57523737355937	bayes_pls_golite062009
DNA binding	3.00143272905695	bayes_pls_golite062009
nucleic acid binding	2.89825020286436	bayes_pls_golite062009
transcription factor activity	2.53664874743748	bayes_pls_golite062009
binding	1.68817361068715	bayes_pls_golite062009
sequence-specific DNA binding	0.46503550280898	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.24108783215685	bayes_pls_golite062009
transcription repressor activity	0.20862059645422	bayes_pls_golite062009
protein binding	0.111941607625758	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: