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View Structure Prediction Details

Protein: cpo-PE
Organism: Drosophila melanogaster
Length: 738 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cpo-PE.

Description E-value Query
Range
Subject
Range
gi|1345457 - gi|1345457|emb|CAA78696.1| Cpo 61.1 [Drosophila melanogaster]
218.0 [0..1] [614..1]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKIANYQDL LGSHHQLLIA ATAAAAAAAA AEPQLQLQHL LPAAPTTPAV ISNPINSIGP  60
   61 INQISSSSHP SNNNQQAVFE KAITISSIAI KRRPTLPQTP ASAPQVLSPS PKRQCAAAVS 120
  121 VLPVTVPVPV PVSVPLPVSV PVPVSVK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.5
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #2
Region A:
Residues: [148-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHPISHTHQI AHTHQISHSH PISHPHHHQL SFAHPTQFAA AVAAHHQQQQ QQQAQQQQQA  60
   61 VQQQQQQAVQ QQQVAYAVAA SPQLQQQQQQ QQHRLAQFNQ AAAAALLNQH LQQQHQAQQQ 120
  121 QHQAQQQSLA HYGGYQLHRY APQQQQQHIL LSSGSSSSKH NSNNNSNTSA GAAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [322-540]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAVPIATSVA AVPTTGGSLP DSPAHESHSH ESNSATASAP TTPSPAGSVT SAAPTATATA  60
   61 AAAGSAAATA AATGTPATSA VSDSNNNLNS SSSSNSNSNA IMENQMALAP LGLSQSMDSV 120
  121 NTASNEEEVR TLFVSGLPMD AKPRELYLLF RAYEGYEGSL LKVTSKNGKT ASPVGFVTFH 180
  181 TRAGAEAAKQ DLQGVRFDPD MPQTIRLEFA KSNTKVSKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.522879
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [541-654]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPQPNTATTA SHPALMHPLT GHLGGPFFPG GPELWHHPLA YSAAAAAELP GAAALQHATL  60
   61 VHPALHPQVP TQMTMPPHHQ TTAIHPGAAM AHMAAAAAAA AAGGGGGAAT AAAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [655-738]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQSAAATAAA AAAASHHHYL SSPALASPAG STNNASHPGN PQIAANAPCS TLFVANLGQF  60
   61 VSEHELKEVF SSHGNSNWLK LLHQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.71
Match: 1u6fA
Description: NMR solution structure of TcUBP1, a single RBD-unit from Trypanosoma cruzi
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 0.0269483316710413 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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