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View Structure Prediction Details

Protein: cpo-PE
Organism: Drosophila melanogaster
Length: 738 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cpo-PE.

Description E-value Query
Range
Subject
Range
gi|1345457 - gi|1345457|emb|CAA78696.1| Cpo 61.1 [Drosophila melanogaster]
218.0 [0..1] [614..1]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKIANYQDL LGSHHQLLIA ATAAAAAAAA AEPQLQLQHL LPAAPTTPAV ISNPINSIGP  60
   61 INQISSSSHP SNNNQQAVFE KAITISSIAI KRRPTLPQTP ASAPQVLSPS PKRQCAAAVS 120
  121 VLPVTVPVPV PVSVPLPVSV PVPVSVK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.5
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #2
Region A:
Residues: [148-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHPISHTHQI AHTHQISHSH PISHPHHHQL SFAHPTQFAA AVAAHHQQQQ QQQAQQQQQA  60
   61 VQQQQQQAVQ QQQVAYAVAA SPQLQQQQQQ QQHRLAQFNQ AAAAALLNQH LQQQHQAQQQ 120
  121 QHQAQQQSLA HYGGYQLHRY APQQQQQHIL LSSGSSSSKH NSNNNSNTSA GAAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [322-540]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAVPIATSVA AVPTTGGSLP DSPAHESHSH ESNSATASAP TTPSPAGSVT SAAPTATATA  60
   61 AAAGSAAATA AATGTPATSA VSDSNNNLNS SSSSNSNSNA IMENQMALAP LGLSQSMDSV 120
  121 NTASNEEEVR TLFVSGLPMD AKPRELYLLF RAYEGYEGSL LKVTSKNGKT ASPVGFVTFH 180
  181 TRAGAEAAKQ DLQGVRFDPD MPQTIRLEFA KSNTKVSKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.522879
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [541-654]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPQPNTATTA SHPALMHPLT GHLGGPFFPG GPELWHHPLA YSAAAAAELP GAAALQHATL  60
   61 VHPALHPQVP TQMTMPPHHQ TTAIHPGAAM AHMAAAAAAA AAGGGGGAAT AAAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [655-738]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQSAAATAAA AAAASHHHYL SSPALASPAG STNNASHPGN PQIAANAPCS TLFVANLGQF  60
   61 VSEHELKEVF SSHGNSNWLK LLHQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.71
Match: 1u6fA
Description: NMR solution structure of TcUBP1, a single RBD-unit from Trypanosoma cruzi
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 0.0269483316710413 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle