YRC Public Data Repository - Protein Structure Prediction

Protein:	ARSR_ECOLI
Organism:	Escherichia coli
Length:	117 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARSR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|192958165, gi... - gi\|75237443\|ref\|ZP_00721476.1\| COG0640: Predicted transcriptional regulators [Escherichia coli E1100...	118.0	[0..1]	[117..1]
Y1325_METJA, YD2... - (Q58721) Putative HTH-type transcriptional regulator MJ1325, Uncharacterized HTH-type transcriptiona... Y1325_METJA - Uncharacterized HTH-type transcriptional regulator MJ1325 OS=Methanocaldococcus jannaschii (strain A... gi\|255051040, gi... - gi\|255051040\|ref\|ZP_05303303.1\| transcriptional regulator, ArsR family [Methanocaldococcus vulcanius...	118.0	[0..1]	[88..1]
gi\|75516036, gi\|... - gi\|75516036\|ref\|ZP_00738154.1\| COG0640: Predicted transcriptional regulators [Escherichia coli 53638... gi\|157162979, gi... - gi\|75197422\|ref\|ZP_00707492.1\| COG0640: Predicted transcriptional regulators [Escherichia coli HS], ... gi\|110616884, gi... - gi\|110807336\|ref\|YP_690856.1\| DNA-binding transcriptional repressor ArsR [Shigella flexneri 5 str. 8... gi\|194431326, gi... - gi\|83571554\|ref\|ZP_00922994.1\| COG0640: Predicted transcriptional regulators [Shigella dysenteriae 1... gi\|124528581, gi... - gi\|124528581\|ref\|ZP_01699859.1\| transcriptional regulator, ArsR family [Escherichia coli B], gi\|1245... gi\|169753197, gi... - gi\|170018269\|ref\|YP_001723223.1\| DNA-binding transcriptional repressor ArsR [Escherichia coli ATCC 8...	117.0	[0..1]	[117..1]
gi\|81247276, gi\|... - gi\|82545865\|ref\|YP_409812.1\| DNA-binding transcriptional repressor ArsR [Shigella boydii Sb227], gi\|...	115.0	[0..1]	[117..1]
gi\|68516169, gi\|... - gi\|68546341\|ref\|ZP_00585889.1\| regulatory protein, ArsR [Shewanella amazonensis SB2B], gi\|68516169\|g...	115.0	[0..3]	[112..6]
gi\|82778677, gi\|... - gi\|82778677\|ref\|YP_405026.1\| DNA-binding transcriptional repressor ArsR [Shigella dysenteriae Sd197]...	115.0	[0..1]	[117..1]
gi\|63255458, gi\|... - gi\|66044751\|ref\|YP_234592.1\| regulatory protein, ArsR [Pseudomonas syringae pv. syringae B728a], gi\|...	115.0	[0..5]	[116..21]
gi\|68541641, gi\|... - gi\|68541641\|ref\|ZP_00581383.1\| regulatory protein, ArsR [Shewanella baltica OS155], gi\|68520700\|gb\|E...	114.0	[0..4]	[116..1]
gi\|30065212, gi\|... - gi\|30065212\|ref\|NP_839383.1\| DNA-binding transcriptional repressor ArsR [Shigella flexneri 2a str. 2...	114.0	[0..6]	[117..3]
gi\|209400520, gi... - gi\|209400520\|ref\|YP_002272969.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str... gi\|217321556, gi... - gi\|217325335\|ref\|ZP_03441419.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str.... gi\|15833627, gi\|... - gi\|15833627\|ref\|NP_312400.1\| DNA-binding transcriptional repressor ArsR [Escherichia coli O157:H7 st... gi\|195935020 - gi\|195935020\|ref\|ZP_03080402.1\| DNA-binding transcriptional repressor ArsR [Escherichia coli O157:H7... gi\|208805667, gi... - gi\|208805667\|ref\|ZP_03248004.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str.... gi\|208812601, gi... - gi\|208812601\|ref\|ZP_03253930.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str.... gi\|208820722, gi... - gi\|208820722\|ref\|ZP_03261042.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str.... gi\|187771520, gi... - gi\|187771520\|gb\|EDU35364.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str. EC4... gi\|254795444, gi... - gi\|254795444\|ref\|YP_003080281.1\| DNA-binding transcriptional repressor [Escherichia coli O157:H7 str... gi\|189002570, gi... - gi\|189002570\|gb\|EDU71556.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str. EC4... gi\|168785353, gi... - gi\|189374298\|gb\|EDU92714.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str. EC8... gi\|189380042, gi... - gi\|189380042\|gb\|EDU98458.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str. EC5... gi\|15833627, gi\|... - gi\|15833627\|ref\|NP_312400.1\| transcriptional repressor of chromosomal ars operon [Escherichia coli O... gi\|188018400, gi... - gi\|188018400\|gb\|EDU56522.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str. EC4... gi\|209755678, gi... - pir\|\|E91175 hypothetical protein ECs4373 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|168753300, gi... - gi\|189359181\|gb\|EDU77600.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str. EC4... gi\|168759571, gi... - gi\|189369750\|gb\|EDU88166.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str. EC4... gi\|12518198, gi\|... - gi\|15804036\|ref\|NP_290072.1\| DNA-binding transcriptional repressor ArsR [Escherichia coli O157:H7 ED... gi\|189364481, gi... - gi\|189364481\|gb\|EDU82900.1\| arsenical resistance operon repressor [Escherichia coli O157:H7 str. EC4...	113.0	[0..1]	[117..1]

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Predicted Domain #1

Region A:
Residues: [1-117]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFLLPIQLF KILADETRLG IVLLLSELGE LCVCDLCTAL DQSQPKISRH LALLRESGLL  60
   61 LDRKQGKWVH YRLSPHIPAW AAKIIDEAWR CEQEKVQAIV RNLARQNCSG DSKNICS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.69897
Match:	1u2wA
Description:	Crystal Structure of the Staphylococcus aureus pI258 CadC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.98990675336286	bayes_pls_golite062009
DNA binding	3.4273272886116	bayes_pls_golite062009
nucleic acid binding	3.38054693035398	bayes_pls_golite062009
transcription factor activity	2.80110428028438	bayes_pls_golite062009
binding	2.18911933843505	bayes_pls_golite062009
transcription activator activity	0.53294679084865	bayes_pls_golite062009
sequence-specific DNA binding	0.53285802828572	bayes_pls_golite062009
transcription repressor activity	0.513853050429619	bayes_pls_golite062009
protein binding	0.035220363090062	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: