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View Structure Prediction Details

Protein: cah-5
Organism: Caenorhabditis elegans
Length: 310 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cah-5.

Description E-value Query
Range
Subject
Range
gi|35505160, gi|... - gi|40363537|ref|NP_954685.1| carbonic anhydrase II [Danio rerio], gi|35505160|gb|AAH57412.1| Carboni...
306.0 [0..25] [280..2]

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Predicted Domain #1
Region A:
Residues: [1-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSHLLVLSL LVALLVVVSC GPGSDHGWGY DENNGPDTWQ GKCQNHLKQS PIDIRAPDVD  60
   61 YALLHRMHFL NYDMDGKIEL SNTGRTLFAG GFESWQHKQP MIQGGGLKHR YKLAQFHLHW 120
  121 GQNDAVGSEH AMGSLHYPAE LHLVHVREGL TLKEALSRPD GLAVVGVFLA KTNDPVANKF 180
  181 SPISERLHDL RHSGNKTELK NFRTKYVLPL DTEAFYRYEG SLTTPDCSEA VIWTVLAEPM 240
  241 AISSHQLHLL RQLHNKELVK SDKNYRPLQP LNGRRIQYRP SKLDRAMICS SFATTSVIIT 300
  301 YVAILSAMLI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.045757
Match: 1ugfA
Description: HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY THR (A65T)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
carbonate dehydratase activity 2.35405414226159 bayes_pls_golite062009
binding 1.59667704693142 bayes_pls_golite062009
protein binding 1.30419076438266 bayes_pls_golite062009
catalytic activity 0.97285738666961 bayes_pls_golite062009
transition metal ion binding 0.36067052386032 bayes_pls_golite062009
carbon-oxygen lyase activity 0.0641135521348118 bayes_pls_golite062009
hydro-lyase activity 0.0479238316186823 bayes_pls_golite062009
lyase activity 0.0337150119314038 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle