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View Structure Prediction Details

Protein: hrp-2
Organism: Caenorhabditis elegans
Length: 611 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hrp-2.

Description E-value Query
Range
Subject
Range
gi|73974148 - gi|73974148|ref|XP_857082.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
323.0 [0..93] [596..2]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEIKQEVK EEAPETTTEA KTEEAAPVAE VVAEVVTNGD KPAENGKTEE PSKYAETENY  60
   61 KKLIGLKMKP ALADVVCEIY ESGLLGPEDL DDRAVDIINS V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [102-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLDQAKFIFT EIKNSELFGV ATKSLYVTSL IRSFKDRCRQ QGAAAVTSGK LINGPELAAL  60
   61 KNLLETTGYT IEVTIGQRKF GGPPPDWEGP ATGPAGQGHE IYVGHIPTDV FEDTLVPLFE 120
  121 KSGKIWDLRL MMDPMSGASR GYAFVTYCNK EDAAAAAKTY DGHEISTGKP LKVN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.045757
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [276-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSIANTRLFI GNIPKTKSKD EILEELKTHA EGVVDVIVYS VPDNEKIKNR GFCFVDFIDH  60
   61 KTASDIKRKI AQHKIRPFNA DVYVDWAEHQ EEPDEDTMSK VKVLYIRNIK EAVTEEKLNE 120
  121 LFKEYASLDR VKKVKDYAFI HFNERDDCLK AMEEWNGKEL EGTVVEASLA KPPQEKKKKP 180
  181 VMRGRGFG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 6.38
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.787118623292657 bayes_pls_golite062009
nucleic acid binding 0.0269483316710413 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [464-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAGGGAGNHG QRGGQRGGGQ WGGNAGPGGY YPNHFNNGYD MPMPWGGGYG GDMGYGAYGG  60
   61 GYGGGYGGPG AYGDFGAYGG GGFRGGMRGS PRGGMGGGGG FRGGPPGRGG MANRRGRGKR 120
  121 PGDGRGGPAS KRDNGKPDFS ADVNMSTF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.154902
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle