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View Structure Prediction Details

Protein: hrp-2
Organism: Caenorhabditis elegans
Length: 611 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hrp-2.

Description E-value Query
Range
Subject
Range
gi|73974148 - gi|73974148|ref|XP_857082.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
323.0 [0..93] [596..2]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEIKQEVK EEAPETTTEA KTEEAAPVAE VVAEVVTNGD KPAENGKTEE PSKYAETENY  60
   61 KKLIGLKMKP ALADVVCEIY ESGLLGPEDL DDRAVDIINS V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [102-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLDQAKFIFT EIKNSELFGV ATKSLYVTSL IRSFKDRCRQ QGAAAVTSGK LINGPELAAL  60
   61 KNLLETTGYT IEVTIGQRKF GGPPPDWEGP ATGPAGQGHE IYVGHIPTDV FEDTLVPLFE 120
  121 KSGKIWDLRL MMDPMSGASR GYAFVTYCNK EDAAAAAKTY DGHEISTGKP LKVN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.045757
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [276-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSIANTRLFI GNIPKTKSKD EILEELKTHA EGVVDVIVYS VPDNEKIKNR GFCFVDFIDH  60
   61 KTASDIKRKI AQHKIRPFNA DVYVDWAEHQ EEPDEDTMSK VKVLYIRNIK EAVTEEKLNE 120
  121 LFKEYASLDR VKKVKDYAFI HFNERDDCLK AMEEWNGKEL EGTVVEASLA KPPQEKKKKP 180
  181 VMRGRGFG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 6.38
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.787118623292657 bayes_pls_golite062009
nucleic acid binding 0.0269483316710413 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [464-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAGGGAGNHG QRGGQRGGGQ WGGNAGPGGY YPNHFNNGYD MPMPWGGGYG GDMGYGAYGG  60
   61 GYGGGYGGPG AYGDFGAYGG GGFRGGMRGS PRGGMGGGGG FRGGPPGRGG MANRRGRGKR 120
  121 PGDGRGGPAS KRDNGKPDFS ADVNMSTF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.154902
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle