YRC Public Data Repository - Protein Structure Prediction

Protein:	SPH1
Organism:	Saccharomyces cerevisiae
Length:	661 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPH1.

Description	E-value	Query Range	Subject Range
SPH1 - Protein involved in shmoo formation and bipolar bud site selection; homologous to Spa2p, localizes t... SPH1_YEAST - Protein SPH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPH1 PE=1 SV=2	0.0	[1..661]	[1..661]
gi\|44982636, gi\|... - gi\|45187852\|ref\|NP_984075.1\| ADL022Cp [Ashbya gossypii ATCC 10895], gi\|44982636\|gb\|AAS51899.1\| ADL02... gi\|44982636 - gi\|44982636\|gb\|AAS51899.1\| ADL022Cp [Ashbya gossypii ATCC 10895]	0.0	[9..401]	[430..836]
gi\|68489072, gi\|... - gi\|68489211\|ref\|XP_711580.1\| hypothetical protein CaO19.6362 [Candida albicans SC5314], gi\|68489072\|... orf19.13719, orf... - SPA2 CGDID:CAL0001359 Assembly 19, Contig19-10246 (40077, 35677) CDS, reverse complemented, translat...	1.0E-54	[194..377]	[522..708]
gi\|32420215, gi\|... - gi\|32420215\|ref\|XP_330551.1\| hypothetical protein [Neurospora crassa], gi\|28926773\|gb\|EAA35738.1\| co... gi\|85116000 - gi\|85116000\|ref\|XP_964974.1\| hypothetical protein NCU03115 [Neurospora crassa OR74A]	3.0E-33	[4..133]	[81..239]
gi\|46108100, gi\|... - gi\|46108100\|ref\|XP_381108.1\| hypothetical protein FG00932.1 [Gibberella zeae PH-1], gi\|42544866\|gb\|E...	2.0E-28	[3..115]	[113..232]
gi\|40740833, gi\|... - gi\|67526715\|ref\|XP_661419.1\| hypothetical protein AN3815.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	4.0E-28	[4..115]	[84..205]

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Predicted Domain #1

Region A:
Residues: [1-124]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISSELTNDQ IIDLISDYKN FKRIIEASVP EDDRRRNQNR QNRNKDLTKL SNVQFWQLTT  60
   61 DVNDELMKRL TDSGADASLN DLDLKRGKAQ SKLSRLKDAK FHKLILDIFT EIERRNLHHL 120
  121 DMGT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [125-381]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HNNGLDEGDL NFYLNDTLFE SFKINDDFMS VNGIISIEVF RELKTQFTLY FQNTLHRIDP  60
   61 VDTTTTRLPI LLETIIKIAK LIGDLLPVLS SVSLQSSLEN EIVYLKSALS HAITSTRYFL 120
  121 TYGDLIPRIV AQSSISEVIF AFCNIAQIVK IKSTSRDDIS RNEGELSDIE AGMKPLKIIE 180
  181 KVKNEKNGKD ISSLGDSGST AVSFPSSGKP ITKKSDMPVV VASPSISIIE KSESSIRESG 240
  241 KVRNNTSGET NLASVSP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [382-553]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKNTKNSSRI TSEPSPREGL PLKVVSNSRS PSPQGNTLPL IGKFRQDYQA SPPKKVITKP  60
   61 VAETAKPYAN IPPAADVLYS PTVTKMRKFR EKVQKFAPNS GLGLRISTSE ENLNNSDVNS 120
  121 TTHNANINNL VEFVESKSMV VLPMAQGILN DVQASKSKLF KSARSVSRLC QN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [554-661]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIEIIPILES VIDMTTKAMV QKSFKLDLGE HCKEIIERLT DCSQKLSELC TYGCDSTKLG  60
   61 KKRFYQKLAD ILMEVTKRTR ELVECVKMAN RQTLSQDLSS FFNYRSVQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.972	N/A	N/A	a.29.3	Acyl-CoA dehydrogenase C-terminal domain-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits