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View Structure Prediction Details

Protein: PUM23_ARATH
Organism: Arabidopsis thaliana
Length: 753 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PUM23_ARATH.

Description E-value Query
Range
Subject
Range
gi|42572079, gi|... - gi|42572079|ref|NP_974130.1| APUM23 (Arabidopsis Pumilio 23); RNA binding / binding [Arabidopsis tha...
466.0 [0..23] [753..1]

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Predicted Domain #1
Region A:
Residues: [1-445]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSVGSKSLP SRRHRTIEED SLMGERGKSS NNHSERNKGM RRKDHKGNRG FDVDSSKKNQ  60
   61 SGGAPNVKPA SKKHSEFEHQ NQFVRKEIDP ETSKYFSEIA NLFDSNEVEL EERSVICGNA 120
  121 LEETRGREYE IATDYIISHV LQTLLEGCEL DQLCSFIRNS ASVFPAIAMD RSGSHVAESA 180
  181 LKSLATHLEN PDAYSVIEEA LHSICKVIVD NPLDMMCNCY GSHVLRRLLC LCKGVSLDSP 240
  241 ELYGAKSSKA LAKRLNLKMS QLDDNNLEIP HQGFPGMLTY LLSGLLSCSR EDMKYLQVDQ 300
  301 YSSLVLQTAL RLMLKQDEQL LEIIPLILRC NSTNKKVEGF HIETNVAKEI LESMKDNSFS 360
  361 HLVEVILEVA PESLYNEMFN KVFKNSLFEL SVDRCANFVI QALISHARDQ EQMGIMWEEL 420
  421 APRFKDLLEQ GKSGVVASLI AVSQR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.69897
Match: 1ib2A
Description: Pumilio 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.47395644967726 bayes_pls_golite062009
RNA binding 1.93705682476038 bayes_pls_golite062009
nucleic acid binding 1.64539435934931 bayes_pls_golite062009
protein binding 1.50566694420704 bayes_pls_golite062009
transcription regulator activity 1.06250847754412 bayes_pls_golite062009
cytoskeletal protein binding 1.03835316513447 bayes_pls_golite062009
DNA binding 0.946847037737779 bayes_pls_golite062009
transcription factor activity 0.362911773502049 bayes_pls_golite062009
actin binding 0.278432079866074 bayes_pls_golite062009
mRNA binding 0.24761043632368 bayes_pls_golite062009
structural molecule activity 0.175046841784998 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [446-753]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQSHENKCCE ALVGAVCSTN ESRISILPRL LFLDYYFGCR DKSTWEWAPG AKMHVMGCLI  60
   61 LQGIFKFSSD HIQPYITSLT SMKAEYITET AKDSSGARVI EAFLASDAAT KQKRRLIIKL 120
  121 RGHFGELSLH TSGSFTVEKC FDACNLTLRE AIASELLDVK VDLSKTKQGP YLLRKLDIDG 180
  181 YASRPDQWKS RQEAKQSTYN EFCSAFGSNK SNFPKNTFVS DASEDAAQEI EVKNTRKEID 240
  241 HHPTSGFKRH REKHAKDKDE PFAGEKRSKQ KKNKTSEATD KPKLAGSKRP FLSGEMTGKN 300
  301 RHSNKMRI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.11
Match: 1ib2A
Description: Pumilio 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.36800795249393 bayes_pls_golite062009
RNA binding 1.78069099517213 bayes_pls_golite062009
nucleic acid binding 1.59410102249793 bayes_pls_golite062009
protein binding 1.3800948965226 bayes_pls_golite062009
transcription regulator activity 1.08645493064764 bayes_pls_golite062009
cytoskeletal protein binding 0.999774819351011 bayes_pls_golite062009
DNA binding 0.956143892328242 bayes_pls_golite062009
transcription factor activity 0.371244009721798 bayes_pls_golite062009
actin binding 0.258516930127328 bayes_pls_golite062009
structural molecule activity 0.174654450621335 bayes_pls_golite062009
mRNA binding 0.107084556647027 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle