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View Structure Prediction Details

Protein: ICDHC_ARATH
Organism: Arabidopsis thaliana
Length: 410 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ICDHC_ARATH.

Description E-value Query
Range
Subject
Range
gi|19171469 - gi|19171469|emb|CAD24782.1| isocitrate dehydrogenase [Arabidopsis thaliana]
434.0 [0..1] [410..1]

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Predicted Domain #1
Region A:
Residues: [1-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFEKIKVAN PIVEMDGDEM TRVIWKSIKD KLITPFVELD IKYFDLGLPH RDATDDKVTI  60
   61 ESAEATKKYN VAIKCATITP DEGRVTEFGL KQMWRSPNGT IRNILNGTVF REPIICKNVP 120
  121 KLVPGWTKPI CIGRHAFGDQ YRATDAVIKG PGKLTMTFEG KDGKTETEVF TFTGEGGVAM 180
  181 AMYNTDESIR AFADASMNTA YEKKWPLYLS TKNTILKKYD GRFKDIFQEV YEASWKSKYD 240
  241 AAGIWYEHRL IDDMVAYALK SEGGYVWACK NYDGDVQSDF LAQGFGSLGL MTSVLVCPDG 300
  301 KTIEAEAAHG TVTRHFRVHQ KGGETSTNSI ASIFAWTRGL AHRAKLDDNA KLLDFTEKLE 360
  361 AACVGTVESG KMTKDLALII HGSKLSRDTY LNTEEFIDAV AAELKERLNA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 120.0
Match: 1lwdA
Description: NADP-dependent isocitrate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
isocitrate dehydrogenase (NAD+) activity 5.9567768649084 bayes_pls_golite062009
isocitrate dehydrogenase activity 5.76817846591752 bayes_pls_golite062009
isocitrate dehydrogenase (NADP+) activity 3.47645456015586 bayes_pls_golite062009
oxidoreductase activity 2.74237430402883 bayes_pls_golite062009
catalytic activity 2.71251959637136 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 2.46799258909805 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2.38235863668553 bayes_pls_golite062009
transferase activity, transferring acyl groups 1.15484868227001 bayes_pls_golite062009
3-isopropylmalate dehydrogenase activity 0.848289435089509 bayes_pls_golite062009
binding 0.530580225668688 bayes_pls_golite062009
protein binding 0.074256700284446 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle