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View Structure Prediction Details

Protein: GNL1_ARATH
Organism: Arabidopsis thaliana
Length: 1443 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GNL1_ARATH.

Description E-value Query
Range
Subject
Range
GNOM_ARATH - ARF guanine-nucleotide exchange factor GNOM OS=Arabidopsis thaliana GN=GN PE=1 SV=1
1372.0 [0..1] [1442..1]

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Predicted Domain #1
Region A:
Residues: [1-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYQNHPSGS NSFHGEFKRC HSKPSKGAVA SMINSEIGAV LAVMRRNVRW GVRYIADDDQ  60
   61 LEHSLIHSLK ELRKQIFSWQ SNWQYVDPRL YIQPFLDVIL SDETGAPITG VALSSVYKIL 120
  121 TLEVFTLETV NVGEAMHIIV DAVKSCRFEV TDPASEEVVL MKILQVLLAC VKSKASNGLS 180
  181 NQDICTIVNT CLRVVHQSSS KSELLQRIAR HTMHELIRCI FSQLPFISPL ANECELHVDN 240
  241 KVGTVDWDPN SGEKRVENGN IASISDTLGT DKDDPSSEMV IPETDLRNDE KKTEVSDDLN 300
  301 AAANGENAMM APYGIPCMVE IFHFLCTLLN VGENGEVNSR SNPIAFDEDV PLFALGLINS 360
  361 AIELGGPSFR EHPKLLTLIQ DDLFCNLMQF GMSMSPLILS TVCSIVLNLY LNLRTELKVQ 420
  421 LEAFFSYVLL RIAQSKHGSS YQQQEVAMEA LVDLCRQHTF IAEVFANFDC DITCSNVFED 480
  481 VSNLLSKNAF PVNGPLSAMH ILALDGLISM VQGMAERVGE ELPASDVPTH EERYEEFWTV 540
  541 RCENYGDPNF W

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.07
Match: 1wa5B
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.267627928716605 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [552-771]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPFVRKVKHI KKKLMLGADR FNRDPNKGLQ YLQGVHLLPE KLDPKSVACF FRYTCGLDKN  60
   61 VMGDFLGNHD QFCIQVLHEF AKTFDFQNMN LATALRLFVG TFKLSGEAQK IHRVLEAFSE 120
  121 RYYEQSPHIL IDKDAAFVLA YSIILLNTDQ HNAQVKTRMT EEDFIRNNRT INGGADLPRE 180
  181 YLSEIYHSIR HSEIQMDEDK GTGFQLMTAS RWISVIYKSK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.0
Match: 1r8mE
Description: SEC7 DOMAIN OF THE ARF EXCHANGE FACTOR ARNO WITH BREFELDIN A-SENSITIZING MUTATIONS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
enzyme regulator activity 0.33175950121636 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.31803821430449 bayes_pls_golite062009
GTPase regulator activity 0.31764113391724 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.19174216196088 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [772-1443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETSPYIQCDA ASHLDRDMFY IVSGPTIAAT SVVFEQAEQE DVLRRCIDGL LAIAKLSAYY  60
   61 HLNSVLDDLV VSLCKFTPFF APLSADEAVL VLGEDARARM ATEAVFLIAN KYGDYISAGW 120
  121 KNILECVLSL NKLHILPDHI ASDAADDPEL STSNLEQEKP SANPVPVVSQ SQPSAMPRKS 180
  181 SSFIGRFLLS FDSEETKPLP SEEELAAYKH ARGIVKDCHI DSIFSDSKFL QAESLQQLVN 240
  241 SLIRASGKDE ASSVFCLELL IAVTLNNRDR ILLIWPTVYE HILGIVQLTL TPCTLVEKAV 300
  301 FGVLKICQRL LPYKENLTDE LLKSLQLVLK LKAKVADAYC ERIAQEVVRL VKANASHVRS 360
  361 RTGWRTIISL LSITARHPEA SEAGFEALRF IMSEGAHLLP SNYELCLDAA SHFAESRVGE 420
  421 VDRSISAIDL MSNSVFCLAR WSQEAKNSIG ETDAMMKLSE DIGKMWLKLV KNLKKVCLDQ 480
  481 RDEVRNHAIS MLQRAIAGAD GIMLPQPLWF QCFDSAVFIL LDDVLTFSIE NSRKTLKKTV 540
  541 EETLVLATKL MSKAFLQSLQ DISQQPSFCR LWVGVLNRLE TYMSTEFRGK RSEKVNELIP 600
  601 ELLKNTLLVM KATGVLLPGD DIGSDSFWQL TWLHVNKISP SLQSEVFPQE ELDQFQRRNA 660
  661 KPEDPPVPGN EV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.23
Match: 2ie3A
Description: No description for 2ie3A was found.

Predicted functions:

Term Confidence Notes
binding 0.267627928716605 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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