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Protein Overview: GNL1_ARATH

General Information:
Name(s) found: GNL1_ARATH [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • ARF guanine-nucleotide exchange factor GNL1 OS=Arabidopsis thaliana GN=GNL1 PE=3 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1443 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: ER body organization [IMP]
    Molecular Function: ARF guanyl-nucleotide exchange factor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYQNHPSGS NSFHGEFKRC HSKPSKGAVA SMINSEIGAV LAVMRRNVRW GVRYIADDDQ  60
   61 LEHSLIHSLK ELRKQIFSWQ SNWQYVDPRL YIQPFLDVIL SDETGAPITG VALSSVYKIL 120
  121 TLEVFTLETV NVGEAMHIIV DAVKSCRFEV TDPASEEVVL MKILQVLLAC VKSKASNGLS 180
  181 NQDICTIVNT CLRVVHQSSS KSELLQRIAR HTMHELIRCI FSQLPFISPL ANECELHVDN 240
  241 KVGTVDWDPN SGEKRVENGN IASISDTLGT DKDDPSSEMV IPETDLRNDE KKTEVSDDLN 300
  301 AAANGENAMM APYGIPCMVE IFHFLCTLLN VGENGEVNSR SNPIAFDEDV PLFALGLINS 360
  361 AIELGGPSFR EHPKLLTLIQ DDLFCNLMQF GMSMSPLILS TVCSIVLNLY LNLRTELKVQ 420
  421 LEAFFSYVLL RIAQSKHGSS YQQQEVAMEA LVDLCRQHTF IAEVFANFDC DITCSNVFED 480
  481 VSNLLSKNAF PVNGPLSAMH ILALDGLISM VQGMAERVGE ELPASDVPTH EERYEEFWTV 540
  541 RCENYGDPNF WVPFVRKVKH IKKKLMLGAD RFNRDPNKGL QYLQGVHLLP EKLDPKSVAC 600
  601 FFRYTCGLDK NVMGDFLGNH DQFCIQVLHE FAKTFDFQNM NLATALRLFV GTFKLSGEAQ 660
  661 KIHRVLEAFS ERYYEQSPHI LIDKDAAFVL AYSIILLNTD QHNAQVKTRM TEEDFIRNNR 720
  721 TINGGADLPR EYLSEIYHSI RHSEIQMDED KGTGFQLMTA SRWISVIYKS KETSPYIQCD 780
  781 AASHLDRDMF YIVSGPTIAA TSVVFEQAEQ EDVLRRCIDG LLAIAKLSAY YHLNSVLDDL 840
  841 VVSLCKFTPF FAPLSADEAV LVLGEDARAR MATEAVFLIA NKYGDYISAG WKNILECVLS 900
  901 LNKLHILPDH IASDAADDPE LSTSNLEQEK PSANPVPVVS QSQPSAMPRK SSSFIGRFLL 960
  961 SFDSEETKPL PSEEELAAYK HARGIVKDCH IDSIFSDSKF LQAESLQQLV NSLIRASGKD1020
 1021 EASSVFCLEL LIAVTLNNRD RILLIWPTVY EHILGIVQLT LTPCTLVEKA VFGVLKICQR1080
 1081 LLPYKENLTD ELLKSLQLVL KLKAKVADAY CERIAQEVVR LVKANASHVR SRTGWRTIIS1140
 1141 LLSITARHPE ASEAGFEALR FIMSEGAHLL PSNYELCLDA ASHFAESRVG EVDRSISAID1200
 1201 LMSNSVFCLA RWSQEAKNSI GETDAMMKLS EDIGKMWLKL VKNLKKVCLD QRDEVRNHAI1260
 1261 SMLQRAIAGA DGIMLPQPLW FQCFDSAVFI LLDDVLTFSI ENSRKTLKKT VEETLVLATK1320
 1321 LMSKAFLQSL QDISQQPSFC RLWVGVLNRL ETYMSTEFRG KRSEKVNELI PELLKNTLLV1380
 1381 MKATGVLLPG DDIGSDSFWQ LTWLHVNKIS PSLQSEVFPQ EELDQFQRRN AKPEDPPVPG1440
 1441 NEV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..551] FFAS03 1.07 Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
    2 View Details [552..771] PSI-BLAST 77.0 SEC7 DOMAIN OF THE ARF EXCHANGE FACTOR ARNO WITH BREFELDIN A-SENSITIZING MUTATIONS
    3 View Details [772..1443] FFAS03 1.23 No description for 2ie3A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.267627928716605 bayes_pls_golite062009
    2
    Term Confidence Notes
  • enzyme regulator activity
    		•  0.33175950121636 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.31803821430449 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.31764113391724 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.19174216196088 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  0.267627928716605 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle