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View Structure Prediction Details

Protein: TIP22_ARATH
Organism: Arabidopsis thaliana
Length: 250 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIP22_ARATH.

Description E-value Query
Range
Subject
Range
gi|115459788, gi... - gi|50927737|ref|XP_473424.1| OSJNBb0034G17.15 [Oryza sativa (japonica cultivar-group)], gi|38605857|...
258.0 [0..1] [243..1]

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Predicted Domain #1
Region A:
Residues: [1-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKIEIGSVG DSFSVASLKA YLSEFIATLL FVFAGVGSAL AFAKLTSDAA LDPAGLVAVA  60
   61 VAHAFALFVG VSIAANISGG HLNPAVTLGL AVGGNITVIT GFFYWIAQCL GSIVACLLLV 120
  121 FVTNGESVPT HGVAAGLGAI EGVVMEIVVT FALVYTVYAT AADPKKGSLG TIAPIAIGFI 180
  181 VGANILAAGP FSGGSMNPAR SFGPAVVSGD FSQIWIYWVG PLVGGALAGL IYGDVFIGSY 240
  241 APAPTTESYP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.522879
Match: 1fqyA
Description: Aquaporin-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
water transmembrane transporter activity 10.3414560257964 bayes_pls_golite062009
water channel activity 10.2169080705067 bayes_pls_golite062009
glycerol transmembrane transporter activity 6.84984722645819 bayes_pls_golite062009
polyol transmembrane transporter activity 6.65010837320829 bayes_pls_golite062009
alcohol transmembrane transporter activity 6.65010837320829 bayes_pls_golite062009
transporter activity 5.23077472964938 bayes_pls_golite062009
substrate-specific channel activity 5.0695479460357 bayes_pls_golite062009
substrate-specific transporter activity 5.06520190871345 bayes_pls_golite062009
passive transmembrane transporter activity 5.06054430984045 bayes_pls_golite062009
channel activity 5.06054430984045 bayes_pls_golite062009
transmembrane transporter activity 4.83314424546299 bayes_pls_golite062009
glycerol channel activity 4.65460547189577 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.82456291801633 bayes_pls_golite062009
pyrimidine transmembrane transporter activity 2.57754311249425 bayes_pls_golite062009
purine transmembrane transporter activity 2.34085190588211 bayes_pls_golite062009
nucleobase transmembrane transporter activity 2.34085190588211 bayes_pls_golite062009
binding 1.09154723976574 bayes_pls_golite062009
ion transmembrane transporter activity 0.516648340085278 bayes_pls_golite062009
urea channel activity 0.449554338632671 bayes_pls_golite062009
urea transmembrane transporter activity 0.449554338632671 bayes_pls_golite062009
amide transmembrane transporter activity 0.449554338632671 bayes_pls_golite062009
active transmembrane transporter activity 0.315342449421593 bayes_pls_golite062009
protein binding 0.179478120921785 bayes_pls_golite062009
cation transmembrane transporter activity 0.141210715822635 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.0368961725897963 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle