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View Structure Prediction Details

Protein: TF2B2_ARATH
Organism: Arabidopsis thaliana
Length: 312 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TF2B2_ARATH.

Description E-value Query
Range
Subject
Range
TF2B_ORYSA - Transcription initiation factor IIB (General transcription factor TFIIB) - Oryza sativa (Rice)
TF2B_ORYSJ - Transcription initiation factor IIB OS=Oryza sativa subsp. japonica GN=TFIIB PE=1 SV=1
gi|125564497 - gi|125564497|gb|EAZ09877.1| hypothetical protein OsI_32170 [Oryza sativa Indica Group]
265.0 [0..1] [312..1]

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Predicted Domain #1
Region A:
Residues: [1-67]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDAFCSDCK RHTEVVFDHS AGDTVCSECG LVLESHSIDE TSEWRTFANE SGDNDPVRVG  60
   61 GPTNPLL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.07
Match: 1rlyA
Description: RDC-derived models of the zinc ribbon domain of human general transcription TFIIB (zinc bound structures)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 5.56373197054355 bayes_pls_golite062009
transcription elongation regulator activity 4.94644536450092 bayes_pls_golite062009
DNA-directed RNA polymerase activity 4.00205139503916 bayes_pls_golite062009
RNA polymerase activity 4.00205139503916 bayes_pls_golite062009
transcription regulator activity 3.26689775782701 bayes_pls_golite062009
nucleic acid binding 2.22680674586367 bayes_pls_golite062009
binding 2.0546846758949 bayes_pls_golite062009
DNA binding 2.01468878668039 bayes_pls_golite062009
positive transcription elongation factor activity 1.49227692053981 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.48570514124545 bayes_pls_golite062009
nucleotidyltransferase activity 1.10975425818967 bayes_pls_golite062009
protein binding 0.549662583711205 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.536637459961958 bayes_pls_golite062009
DNA primase activity 0.494157804587957 bayes_pls_golite062009
catalytic activity 0.433059249914853 bayes_pls_golite062009
RNA polymerase II transcription elongation factor activity 0.0384907163875292 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [68-312]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADGGLTTVIS KPNGSSGDFL SSSLGRWQNR GSNPDRGLIV AFKTIATMAD RLGLVATIKD  60
   61 RANEIYKRVE DQKSSRGRNQ DALLAACLYI ACRQEDKPRT VKEICSVANG ATKKEIGRAK 120
  121 EYIVKQLGLE TGQLVEMGTI HAGDFMRRFC SNLGMTNQTV KAAQESVQKS EEFDIRRSPI 180
  181 SIAAAVIYII TQLSDEKKPL RDISVATGVA EGTIRNSYKD LYPHLSKIIP AWYAKEEDLK 240
  241 NLQSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.69897
Match: 1c9bA
Description: Transcription factor IIB (TFIIB), core domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 6.34389570239956 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 3.19553060844126 bayes_pls_golite062009
protein kinase regulator activity 2.87088741581791 bayes_pls_golite062009
transcription regulator activity 2.795846725429 bayes_pls_golite062009
binding 2.4204867358489 bayes_pls_golite062009
nucleic acid binding 2.04886889839181 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.00665312545368 bayes_pls_golite062009
DNA binding 1.94297811210385 bayes_pls_golite062009
transcription elongation regulator activity 1.69439693414478 bayes_pls_golite062009
kinase regulator activity 1.65109787211976 bayes_pls_golite062009
protein binding 1.47106731485576 bayes_pls_golite062009
transcription factor activity 1.21921365719206 bayes_pls_golite062009
transcription factor binding 0.749278791251235 bayes_pls_golite062009
enzyme regulator activity 0.729629809946521 bayes_pls_golite062009
positive transcription elongation factor activity 0.42590121577004 bayes_pls_golite062009
transcription coactivator activity 0.138191616709499 bayes_pls_golite062009
transcription activator activity 0.0696060248241566 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle