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View Structure Prediction Details

Protein: nas-31
Organism: Caenorhabditis elegans
Length: 578 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-31.

Description E-value Query
Range
Subject
Range
nas-31 - status:Partially_confirmed UniProt:Q7JLI1 protein_id:CAE48502.1
422.0 [0..1] [577..1]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILQLLFYSL FTHLAVSQID VNQALNQNKL NIDTISSSAI SDAELEKTFP RTNLSRMRNA  60
   61 LKSLRQNWSA KLQAMPARNY QNAGTNQENG ATEQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [95-358]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKPLREKPRD RVKMEGDTLH QVNKAAGLND ILYQGDMVLT DDQIATILEA RDETTVSTAS  60
   61 RARRQAYRDR YYPSTTWGSS VYYYYDRTAT PKIVKAFEQA VAFWQNVTCI NIMQSSTAIN 120
  121 RIRVFKGQGC YSYVGRISGV QDLSLGTGCE EFGTAAHELG HALGFFHTQS RYDRDNYISI 180
  181 NYANIDPSYV EQFDKETSNT NFNYGMPYDY GSIMQYGATS ASSNDKATMI ARDTEYQDTM 240
  241 GSDFVGFYDI SMMNEHYKCK ELCP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.045757
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.361128926739778 bayes_pls_golite062009
hydrolase activity 0.29183147920977 bayes_pls_golite062009
peptidase activity 0.23695590197447 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.0341081586881899 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [359-578]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AASSAQCKNG GFPSPRNCAI CICPSGYGGI LCDQRPPGCG DSVTATTTWQ TLTNTIGDGL  60
   61 PTLRDNHTMC NYWVKAPDNQ AVEIRISGLT TVTIDGCIFG GVEIKTHKDQ KLTGYRYCSS 120
  121 ADQNTVHRST GSLVPIILFN RYASTKAVLE YRAVTPSVDV SATYTTFAPI VNSCQDLHPN 180
  181 CAAYAWNGFC VNPFYSMQAR HYYCAYTCGL CWMNNNNNFY 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.09691
Match: 1nt0A
Description: Mannose-binding protein associated serine protease 2, MASP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.286076792172079 bayes_pls_golite062009
protein binding 0.14494900666454 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle