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View Structure Prediction Details

Protein: hil-2
Organism: Caenorhabditis elegans
Length: 173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hil-2.

Description E-value Query
Range
Subject
Range
hil-2 - histone H1.2 status:Partially_confirmed UniProt:P15796 protein_id:AAM44399.1
196.0 [0..1] [171..1]

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Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPFPFSRLFS FGVEHETGYV SRQSGRGRVY KGGGYSPFTI TFQVSTHRST MSDVTVAETP  60
   61 AVKTPTKAPK APKSKTTKEP KAKV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [85-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAAHPPFINM VTAAATKKPV AKKPVAKKAA TGEKKAKKTT VAKKTGDKVK KAKSPKKIAK  60
   61 PAAKKVAKSP AKKAAPKKAP AKKAAAPKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.045757
Match: 1hstA
Description: Histone H5, globular domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.835523092977445 bayes_pls_golite062009
transcription regulator activity 0.4843036104266 bayes_pls_golite062009
nucleic acid binding 0.37117756729668 bayes_pls_golite062009
DNA binding 0.3118855114645 bayes_pls_golite062009

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