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View Structure Prediction Details

Protein: pdfr-1
Organism: Caenorhabditis elegans
Length: 546 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pdfr-1.

Description E-value Query
Range
Subject
Range
pdfr-1 - status:Confirmed UniProt:Q6W3C2 protein_id:AAT92086.1
287.0 [0..1] [540..1]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADATSPFNV SILDNSTKLS EMVESGWNVL ASTSVQAFNE AMDVLEESYP LCKKMLDHNN  60
   61 LFPERDPNDT RIWCNATYDT VLCWPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.522879
Match: 1ijyA
Description: Frizzled 8 (FZ8)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transmembrane receptor activity 4.38708793497137 bayes_pls_golite062009
receptor activity 4.1046853496316 bayes_pls_golite062009
signal transducer activity 3.17034085692897 bayes_pls_golite062009
molecular transducer activity 3.17034085692897 bayes_pls_golite062009
Wnt receptor activity 2.95244120669902 bayes_pls_golite062009
binding 2.18217693324765 bayes_pls_golite062009
protein binding 2.15165760199286 bayes_pls_golite062009
Wnt-protein binding 2.04664201899031 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [87-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPANSSVTLQ CPHMKGLDPN KNITKDCHVS GVWSGRNAGE MGPTLPGWTN FTM

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.84
Match: 1u34A
Description: 3D NMR structure of the first extracellular domain of CRFR-2beta, a type B1 G-protein coupled receptor
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [140-546]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CYTDEVIYIM QNLNNESLTI AQEVARNARK LEFVGLGLSL VSLILAISIF SYFRRLRVFR  60
   61 NLLHLHLMIA MLMVVILRLV LYIDLIFTGE NGPHTNSAEG KTINTMPIVC EGMFFFLEYF 120
  121 KTVTFCWMFL EGIYLNNQIV FGFFNSEPKL LPYFIAGYGI PLVHTMLWLL VVLIKKDFKV 180
  181 ERCLGSYYLE PEFWILDGPR MAELVINLFF ICNVIRVLYS KVRESNNTSE AGLKKSVKAA 240
  241 MMLLPLLGVP NIMQTIPFAP TRDNIMVFAV WTYTASFTYM YQGLMVASIY CFTNKEVNHV 300
  301 LKTFYARYRL LHKSQNELRR GSRSVASHYA AKNGTANASA PQTNNADEFG KLSPFPSRSK 360
  361 KGSDDSTTKL MKDAVMEEEK NANNNGYGSA GEMTPLREGS NRSTKSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.69897
Match: 1f88A
Description: Rhodopsin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle