YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: ptb-1
Organism: Caenorhabditis elegans
Length: 615 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ptb-1.

Description E-value Query
Range
Subject
Range
gi|114674372 - gi|114674372|ref|XP_001172084.1| PREDICTED: polypyrimidine tract-binding protein 1 [Pan troglodytes]
319.0 [0..63] [615..390]

Back

Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKRGPDDLQ LSLRNGVGGA STTAPGVAAA AYYANVMTAD SEPKKAKLDP TLYSSQFYTP  60
   61 AMHHGLMTAD ASTVAAVTAA ANATTAQLLT GNPITQIQGI QLSTLPQCNS TSAV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [115-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSIPVSKVVH VRNIPPDLVD VELMQLCIQY GPVSNYMMLK GKSQAFVEYE EEASAAAFVS  60
   61 GMTAVPIQIR GRTLFAQYST HRELKFDKNK AISDTESVAN GSVSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.09691
Match: 2cq1A
Description: solution structure of RNA binding domain in PTB-like protein L
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [220-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEVGTQQQPN SVLRTIIENM MFPVSLDVLY QLFTRYGKVL RIITFNKNNT FQALVQMSEA  60
   61 NSAQLAKQGL ENQNVYNGCC TLRIDYSKLS TLNVKYNNDK SRDYTNPNLP AGEMTLEQTI 120
  121 AMSIPGLQNL IPANPYNFAF GANPATTFLT TQLAASTAAA AAVNDSANAA ALAPYLNPLG 180
  181 LTSANLAPSI SSMRFPMI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 2adbA
Description: Solution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [418-615]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLTPVILVSN LHEMKVTTDA LFTLFGVYGD VMRVKILYNK KDNALIQYSE PQQAQLALTH  60
   61 LDKVKWHDRL IRVAPSKHTN VQMPKEGQPD AGLTRDYAHS TLHRFKKPGS KNYLNIYPPC 120
  121 ATLHLSNIPT SVSEEKLKEM FAEAGFAVKA FKFFPKDHKM ALCQLEDIET AIDALIAMHN 180
  181 HKLAENAHLR VSFSKSGI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.0
Match: 2adcA
Description: Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.15097136329571 bayes_pls_golite062009
mRNA binding 4.05281507540116 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
2.83802439076672 bayes_pls_golite062009
poly-pyrimidine tract binding 1.69629099229571 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
snRNA binding 0.249682711188639 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle