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Protein Overview: ptb-1

General Information:
Name(s) found: ptb-1 / CE30508 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00004207 locus:ptb-1 status:Confirmed UniProt:Q18999 protein_id:CAA85411.3 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 615 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: mRNA processing [IEALink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKRGPDDLQ LSLRNGVGGA STTAPGVAAA AYYANVMTAD SEPKKAKLDP TLYSSQFYTP  60
   61 AMHHGLMTAD ASTVAAVTAA ANATTAQLLT GNPITQIQGI QLSTLPQCNS TSAVTSIPVS 120
  121 KVVHVRNIPP DLVDVELMQL CIQYGPVSNY MMLKGKSQAF VEYEEEASAA AFVSGMTAVP 180
  181 IQIRGRTLFA QYSTHRELKF DKNKAISDTE SVANGSVSNF EVGTQQQPNS VLRTIIENMM 240
  241 FPVSLDVLYQ LFTRYGKVLR IITFNKNNTF QALVQMSEAN SAQLAKQGLE NQNVYNGCCT 300
  301 LRIDYSKLST LNVKYNNDKS RDYTNPNLPA GEMTLEQTIA MSIPGLQNLI PANPYNFAFG 360
  361 ANPATTFLTT QLAASTAAAA AVNDSANAAA LAPYLNPLGL TSANLAPSIS SMRFPMINLT 420
  421 PVILVSNLHE MKVTTDALFT LFGVYGDVMR VKILYNKKDN ALIQYSEPQQ AQLALTHLDK 480
  481 VKWHDRLIRV APSKHTNVQM PKEGQPDAGL TRDYAHSTLH RFKKPGSKNY LNIYPPCATL 540
  541 HLSNIPTSVS EEKLKEMFAE AGFAVKAFKF FPKDHKMALC QLEDIETAID ALIAMHNHKL 600
  601 AENAHLRVSF SKSGI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] deduced N/A No confident structure predictions are available.
    2 View Details [115..219] PSI-BLAST 16.09691 solution structure of RNA binding domain in PTB-like protein L
    3 View Details [220..417] PSI-BLAST 17.0 Solution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA
    4 View Details [418..615] PSI-BLAST 41.0 Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • RNA binding
    		•  5.15097136329571 bayes_pls_golite062009
  • mRNA binding
    		•  4.05281507540116 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.81920018903278 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
    		• 2.83802439076672 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  1.69629099229571 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  1.46469774223879 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.07788694919471 bayes_pls_golite062009
  • DNA binding
    		•  0.978604858165557 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.591700155096213 bayes_pls_golite062009
  • snRNA binding
    		•  0.249682711188639 bayes_pls_golite062009
  • transcription factor activity
    		•  0.234742017105535 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.55

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle