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View Structure Prediction Details

Protein: wrs-2
Organism: Caenorhabditis elegans
Length: 650 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wrs-2.

Description E-value Query
Range
Subject
Range
gi|187022810, gi... - gi|39586534|emb|CAE73661.1| Hypothetical protein CBG21169 [Caenorhabditis briggsae], gi|187022810|em...
gi|157776612 - gi|157776612|ref|XP_001666372.1| hypothetical protein CBG21169 [Caenorhabditis briggsae AF16]
470.0 [0..1] [650..1]

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Predicted Domain #1
Region A:
Residues: [1-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTYVAEIGE IVRSQRRDEE YIEDITERLS RVSKELLGQR TWIRWFPYLK SIASTLYYTS  60
   61 TVVLGNQTLG EEYVHLFESN GLERTVPSIP SRISFVLLHS AFPLISNYLI QKAESTLTHP 120
  121 STESFLGIPI RKNQKARQSF LDVFFWLRTK LFPQLQRAHI ALFYITGAYY SIARRFTGIR 180
  181 FLSASAHSDI P

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 5.075721
Match: PF04757.5
Description: No description for PF04757.5 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [192-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALKVYRFLGY ITLIQLAVSI GISLYSFLEQ EKFNNKLKKE KKENNGGSDR NLDENSLFHP  60
   61 TFQCSICLEN KNPSALFCGH LFCWTCIQEH AVAATSSAST SSARCPQCRL EFQPRDP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1z6uA
Description: Np95-like ring finger protein isoform b [Homo sapiens]
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [309-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNLRLLSTST HPTIYFTGIQ PTGIPHLGNF FGSIEPWTEL QNSVDKNILM MLSVVDQHAI  60
   61 SLGPLPANEL RQNTHQMTAS LIACGVDPNR TLLFRQSDVP QIAQISWILG SLQTTSKLAR 120
  121 LPQYKEKKER FKKGDIPVGL LTYPLLQAAD VLTFKATTVP VGEDQSQHLN LLGGLAYAFN 180
  181 KTYETEIFPI PKQLTRESHA RIRSLREPEK KMSKSSGGPR SRIEITDSRS TIIEKCQKAQ 240
  241 SDNAGKVTYD KENRLAVSNL LDLYSAVTKT QTSEIDFSNW TTLDLKMNLA EAVDKRLAPI 300
  301 RQKFEELQNT GEVDKVLTEN GEKAREIAEK NLEEIRRTIG FL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.69897
Match: 1i6kA
Description: Tryptophanyl-tRNA synthetase (TrpRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming aminoacyl-tRNA and related compounds 7.16276509815667 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 7.16276509815667 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.13957775963187 bayes_pls_golite062009
ligase activity 6.11211476973434 bayes_pls_golite062009
tryptophan-tRNA ligase activity 5.34430928486195 bayes_pls_golite062009
glutamate-tRNA ligase activity 2.63681738794687 bayes_pls_golite062009
methionine-tRNA ligase activity 2.56893064485672 bayes_pls_golite062009
catalytic activity 2.37674226834122 bayes_pls_golite062009
tyrosine-tRNA ligase activity 1.88984817882585 bayes_pls_golite062009
arginine-tRNA ligase activity 1.50161401062914 bayes_pls_golite062009
cysteine-tRNA ligase activity 0.844943947059557 bayes_pls_golite062009
signal transducer activity 0.577197533814178 bayes_pls_golite062009
molecular transducer activity 0.577197533814178 bayes_pls_golite062009
nucleotidyltransferase activity 0.513380816431376 bayes_pls_golite062009
binding 0.485102284225571 bayes_pls_golite062009
nucleic acid binding 0.449504767632354 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.126511747475258 bayes_pls_golite062009
glutamine-tRNA ligase activity 0.118292082006187 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle