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View Structure Prediction Details

Protein: div-1
Organism: Caenorhabditis elegans
Length: 581 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for div-1.

Description E-value Query
Range
Subject
Range
gi|114638538, gi... - gi|114638540|ref|XP_001169495.1| PREDICTED: polymerase (DNA directed), alpha 2 (70kD subunit) isofor...
521.0 [0..7] [581..5]

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Predicted Domain #1
Region A:
Residues: [1-144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYEFDLEDF NDNLEPFGFN CPAKDHFIEK LEGLCKTFRK SGEDIVDDVV SVMSNLGQKS  60
   61 VDSGILAKLE ENLEAQAQKT VHTPRSVKKP ARGRVPLAEK SGFILSGDPD DIEKPSHHLT 120
  121 NSAIAKLEGH FLDFSPFPGS PANE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [145-253]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFLKRADPSH VVTTIRGKKY QDKGLKGSTK SDDTIRIISK TPSTLYGGDK SSMVIEAKAQ  60
   61 RMADIAHRIQ KSFEEIVDWG NPSIPSVDVV YTYGQVIHDE TKDNEKFGE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [254-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSVALMINDE DGTMIRMDFS KMTEDITLFP GQIIAVRGTN ETGEELQVDK IFQPAALPVN  60
   61 PVETDTTKEI WFACGPYTAT DNCGYEHLCE LLDKVVAEKP DILMLAGPFV DKKNTFLNKP 120
  121 TFNITYDNLL EDLLLKVKET LVGTKTQVII QPNASRDLCV PPVFPSAPFQ QNRKLDKIKK 180
  181 ELIFVADPCI FRISGVEVAM TSSEPIQALS NTEFHRSANQ ENIDRVARLS SHLLTQQCMY 240
  241 PLEPTEVPAS MGDLLDVCCI GSTPHIVFAP TKLAPSAKCV NGSVFINSST LAKGPTGNYA 300
  301 KMSINLNAGE LMPGETVADY AQIQILKI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.7
Match: 2a22A
Description: Structure of Vacuolar Protein Sorting 29 from Cryptosporidium Parvum
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 1.92175568522677 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.74029033853014 bayes_pls_golite062009
catalytic activity 1.30037658165549 bayes_pls_golite062009
protein serine/threonine phosphatase activity 1.17916462117542 bayes_pls_golite062009
binding 0.908738313033381 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.768201004870964 bayes_pls_golite062009
transporter activity 0.738056916803442 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.463083693607652 bayes_pls_golite062009
protein binding 0.32656262395659 bayes_pls_golite062009
phosphatase activity 0.325160962990544 bayes_pls_golite062009
structural molecule activity 0.211411396269789 bayes_pls_golite062009
substrate-specific transporter activity 0.179830790414814 bayes_pls_golite062009
protein transporter activity 0.0516488968911069 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle