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View Structure Prediction Details

Protein: mig-5
Organism: Caenorhabditis elegans
Length: 625 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mig-5.

Description E-value Query
Range
Subject
Range
mig-5 - presynaptic density protein (PSD-95) repeat-like domain status:Confirmed UniProt:O61720 protein_id:C...
430.0 [0..1] [625..1]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPPCTSDCS QIKVFYYLDD ETTPYVSVIE AREGVATLGN FKNSFTKRGY KYYAKELDPD  60
   61 IQREVKVELT TDSDRLRKSQ NGFYEIFLVS TPGYGTLPRN SGT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 1wspA
Description: Crystal structure of axin dix domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [104-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRPQRTALD KRRRRSADFD ATPYSDASLA PSTIVSRRAG EHLAELYTSN SEDPYQYDEH  60
   61 TRRTGDDS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [172-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLYEPLAARD MNKIYDDDRR RKKQKKERFR RPYVPSTISS ATESSVNSGL PRILEIYLPM  60
   61 KNVPYLGLSV CTIDGHIFVS EIAPEGAVEK DGRVNVGDQI LQVNRVSFEE LSGPQAVRSL 120
  121 REAASSKRQN TEKMKALGLD PQEQTATTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1z87A
Description: solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [321-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDGTLPFTST ASDDEERMLY DQRRNGIPRA LIEEAERKRE NEQNEKIEQL TEMIDPIIVV  60
   61 RSMARPDSGL AVKNRKWLKI LVPMSFIGRD LVDWLVDHMA DIHNRKKARI YAARLLAAGL 120
  121 IRHVVSKLTF TEKCYYVFGD GILGNDRNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.154902
Match: 1fshA
Description: Segment polarity protein Dishevelled-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.04426015975991 bayes_pls_golite062009
binding 1.99063774159045 bayes_pls_golite062009
DNA binding 1.63968725174405 bayes_pls_golite062009
nucleic acid binding 1.51035375793093 bayes_pls_golite062009
transcription factor activity 1.16072080355661 bayes_pls_golite062009
transcription activator activity 0.14130464856269 bayes_pls_golite062009
sequence-specific DNA binding 0.13573040816325 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [470-625]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDTTGTSGTT MRVEATTEVT YVGSPAPHAL AARVGRNIPH RLETTTLSPV AHDQTWLRRR  60
   61 RDCESPMTND YASMVGESQI GMNPVGNYHV FGTKNNHRQV PAPSQVTSSS LTNVTNSRKW 120
  121 WLRRPSADSS IQYYGSSSFS DSVAERSQPR FRRGEQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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