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View Structure Prediction Details

Protein: coh-4
Organism: Caenorhabditis elegans
Length: 609 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for coh-4.

Description E-value Query
Range
Subject
Range
coh-3 - status:Partially_confirmed UniProt:Q19232 protein_id:CAB01150.2
1016.0 [0..1] [609..1]

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Predicted Domain #1
Region A:
Residues: [1-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVISIDVPLK ASEEATVKFL LGIVFGSHKK LGLQSNRREC LRHDVLQASK LIHWILRNEK  60
   61 KNRRSLSVAC NLVYGNTIVL STQVARLLHD AIRARDIVAF TSYMAQEEER KRKTREQMEG 120
  121 DNSNKTPKKK RRQAEEFPLA PTPISVALRQ NITMPDVLSV HKNDQINVED DLAAPTMEQL 180
  181 EMMYGMLESE NR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [193-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTAIDLTFID RYSFNDARQN VHNLNLNMET DFQRPSDDFI RSQLMTPTKS IPQEEEVFQP  60
   61 ATHLKDVLRF AHLPIALDET ERRRSMDEEM EEARNSGINT EFLTPQQMNV PRIASEILEL 120
  121 DDEV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [317-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIPRTIPKAP HSATKNQMAE NEGAEEGINY KIPLRDMHHL MEDYSSLHFK DVEPLCRKTS  60
   61 KVMNLKDLLN PIPYYLRKGC NTDMWDLFKV KTRKFDSTIG RHDVSDTEDE DEEAERRNRR 120
  121 EAERELLETI DLSQMKFMAT PLKEKSPIMT PAH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [470-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPEEIEFREE LEVPRLEQFE PMNVNPISPR MDEPALLEEN WNSKPTWSNP ISENIADALT  60
   61 IRANIIHKLN SECPYEVTLD SIIPLAATSR REAARTFYTV LELLKEREIK AIQRDPYGNI 120
  121 DLLLSTDDIE DIDELAMADF 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.61
Match: 1w1wE
Description: Sc Smc1hd:Scc1-C complex, ATPgS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.683379929086364 bayes_pls_golite062009
transcription regulator activity 0.16959343932447 bayes_pls_golite062009
nucleic acid binding 0.0949481158963694 bayes_pls_golite062009
DNA binding 0.00746597740509714 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle