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View Structure Prediction Details

Protein: feh-1
Organism: Caenorhabditis elegans
Length: 691 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for feh-1.

Description E-value Query
Range
Subject
Range
feh-1 - status:Confirmed UniProt:Q8IA97 protein_id:AAN84831.1
383.0 [0..82] [691..52]

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Predicted Domain #1
Region A:
Residues: [1-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDFTPVYLL FSFIISSLQI IPVEEQCSKT CITLSLGTCK QQKKKKNLYS DLACRKNVDI  60
   61 FIIYVSFEKK KEIFLEFFHH VLQEEHDEYS AFKEAYEEEE SREYVIENGV KRLVNQHYDS 120
  121 RGY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [124-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSAGRGQKGR REEERRRNMA VDYSSQDFRQ SLAAIDQASR DGAISRGEDG VRVRQIGDTT  60
   61 IMTEHRDPYS FYWQLDQARR EAESPPRRPP PTDYVIDEEE EVLETVYSPE ADDVMFENQY 120
  121 RRPVRHPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [252-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPPPIMEEE PKDLPPGWEK HEDPQGYSYY WHVDSGTIQR QPPPPVRDVT PARSPSPPPL  60
   61 PPPITTANRE TQADAPPPQI IQLPPQQPVI EEHAFKQTTT KRRIEQDEMS EREIEDVAMI 120
  121 ENGDTYHKPV RFAVRSLGWT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.30103
Match: 2f21A
Description: No description for 2f21A was found.

Predicted Domain #4
Region A:
Residues: [392-448]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DISEDELTAE KSSRAVNRAI VDLTTRSDID SIPKWGDGRE LIMELDDNEL ALLDPDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 1tk7A
Description: NMR structure of WW domains (WW3-4) from Suppressor of Deltex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.845797520024653 bayes_pls_golite062009
protein binding 0.773483173957116 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [449-529]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVIHSERIQ AIRVWGVGRD NGRDFAYVSR DRGTRRFMCH VFRCDTSAKT IANTLRDICK  60
   61 RLMLHRRPSS LHAIESGEKR I

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.0
Match: 1m7eA
Description: Crystal structure of the phosphotyrosine binding domain(PTB) of mouse Disabled 2(Dab2):implications for Reeling signaling
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [530-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VRSEGLTAPI DEPRKVIRCH FLGVTQVPKA TGIEILNEAV DRLVSQVRSE RWILADVSIA  60
   61 PSTIAIVEVN GQQIAECRVR YLSFLGIGRD VKHCAFIMQT SSESFMCYVF HVEPNAAAMA 120
  121 KMVEAACKLR YQKVLDAHSS SRHHSGMSIH GQHPPSTYHG MD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.221849
Match: 1wguA
Description: Solution Structure of the C-terminal Phosphotyrosine Interaction Domain of APBB2 from Mouse
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.5144141194236 bayes_pls_golite062009
protein binding 1.42613583294271 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle