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View Structure Prediction Details

Protein: feh-1
Organism: Caenorhabditis elegans
Length: 691 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for feh-1.

Description E-value Query
Range
Subject
Range
feh-1 - status:Confirmed UniProt:Q8IA97 protein_id:AAN84831.1
383.0 [0..82] [691..52]

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Predicted Domain #1
Region A:
Residues: [1-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDFTPVYLL FSFIISSLQI IPVEEQCSKT CITLSLGTCK QQKKKKNLYS DLACRKNVDI  60
   61 FIIYVSFEKK KEIFLEFFHH VLQEEHDEYS AFKEAYEEEE SREYVIENGV KRLVNQHYDS 120
  121 RGY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [124-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSAGRGQKGR REEERRRNMA VDYSSQDFRQ SLAAIDQASR DGAISRGEDG VRVRQIGDTT  60
   61 IMTEHRDPYS FYWQLDQARR EAESPPRRPP PTDYVIDEEE EVLETVYSPE ADDVMFENQY 120
  121 RRPVRHPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [252-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPPPIMEEE PKDLPPGWEK HEDPQGYSYY WHVDSGTIQR QPPPPVRDVT PARSPSPPPL  60
   61 PPPITTANRE TQADAPPPQI IQLPPQQPVI EEHAFKQTTT KRRIEQDEMS EREIEDVAMI 120
  121 ENGDTYHKPV RFAVRSLGWT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.30103
Match: 2f21A
Description: No description for 2f21A was found.

Predicted Domain #4
Region A:
Residues: [392-448]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DISEDELTAE KSSRAVNRAI VDLTTRSDID SIPKWGDGRE LIMELDDNEL ALLDPDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 1tk7A
Description: NMR structure of WW domains (WW3-4) from Suppressor of Deltex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.845797520024653 bayes_pls_golite062009
protein binding 0.773483173957116 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [449-529]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVIHSERIQ AIRVWGVGRD NGRDFAYVSR DRGTRRFMCH VFRCDTSAKT IANTLRDICK  60
   61 RLMLHRRPSS LHAIESGEKR I

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.0
Match: 1m7eA
Description: Crystal structure of the phosphotyrosine binding domain(PTB) of mouse Disabled 2(Dab2):implications for Reeling signaling
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [530-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VRSEGLTAPI DEPRKVIRCH FLGVTQVPKA TGIEILNEAV DRLVSQVRSE RWILADVSIA  60
   61 PSTIAIVEVN GQQIAECRVR YLSFLGIGRD VKHCAFIMQT SSESFMCYVF HVEPNAAAMA 120
  121 KMVEAACKLR YQKVLDAHSS SRHHSGMSIH GQHPPSTYHG MD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.221849
Match: 1wguA
Description: Solution Structure of the C-terminal Phosphotyrosine Interaction Domain of APBB2 from Mouse
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.5144141194236 bayes_pls_golite062009
protein binding 1.42613583294271 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle