| Protein: | daf-3 |
| Organism: | Caenorhabditis elegans |
| Length: | 796 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
|
Region A: Residues: [1-118] |
1 11 21 31 41 51
| | | | | |
1 MKLIATSLLV PDEHTPMMSP VNTTTKILQR SGIKMEIPPY LDPDSQDDDP EDGVNYPDPD 60
61 LFDTKNTNMT EYDLDVLKLG KPAVDEARKK IEVPDASAPP NKIVEYLMYY RTLKESEL
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [119-248] |
1 11 21 31 41 51
| | | | | |
1 IQLNAYRTKR NRLSLNLVKN NIDREFDQKA CESLVKKLKD KKNDLQNLID VVLSKGTKYT 60
61 GCITIPRTLD GRLQVHGRKG FPHVVYGKLW RFNEMTKNET RHVDHCKHAF EMKSDMVCVN 120
121 PYHYEIVIGT
|
| Detection Method: | |
| Confidence: | 47.0 |
| Match: | 1mhdA |
| Description: | SMAD MH1 domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [249-357] |
1 11 21 31 41 51
| | | | | |
1 MIVGQRDHDN RDMPPPHQRY HTPGRQDPVD DMSRFIPPAS IRPPPMNMHT RPQPMPQQLP 60
61 SVGATFAHPL PHQAPHNPGV SHPYSIAPQT HYPLNMNPIP QMPQMPQMP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [358-525] |
1 11 21 31 41 51
| | | | | |
1 PPLHQGYGMN GPSCSSENNN PFHQNHHYND ISHPNHYSYD CGPNLYGFPT PYPDFHHPFN 60
61 QQPHQPPQLS QNHTSQQGSH QPGHQGQVPN DPPISRPVLQ PSTVTLDVFR RYCRQTFGNR 120
121 FFEGESEQSG AIIRSSNKFI EEFDSPICGV TVVRPRMTDG EVLENIMP
|
| Detection Method: | |
| Confidence: | 5.69897 |
| Match: | 1m2vB |
| Description: | Sec24 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [526-796] |
1 11 21 31 41 51
| | | | | |
1 EDAPYHDICK FILRLTSESV TFSGEGPEVS DLNEKWGTIV YYEKNLQIGE KKCSRGNFHV 60
61 DGGFICSENR YSLGLEPNPI REPVAFKVRK AIVDGIRFSY KKDGSVWLQN RMKYPVFVTS 120
121 GYLDEQSGGL KKDKVHKVYG CASIKTFGFN VSKQIIRDAL LSKQMATMYL QGKLTPMNYI 180
181 YEKKTQEELR REATRTTDSL AKYCCVRVSF CKGFGEAYPE RPSIHDCPVW IELKINIAYD 240
241 FMDSICQYIT NCFEPLGMED FAKLGINVSD D
|
| Detection Method: | |
| Confidence: | 79.69897 |
| Match: | 1dd1A |
| Description: | Smad4 tumor suppressor C-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.31656652567204 | bayes_pls_golite062009 |
| transcription regulator activity | 1.93348471274042 | bayes_pls_golite062009 |
| protein binding | 1.67660511831067 | bayes_pls_golite062009 |
| DNA binding | 1.64107635602436 | bayes_pls_golite062009 |
| nucleic acid binding | 1.59899290578262 | bayes_pls_golite062009 |
| transforming growth factor beta receptor, cytoplasmic mediator activity | 0.7615469625125 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.59091508757448 | bayes_pls_golite062009 |
| transcription factor activity | 0.554078523633227 | bayes_pls_golite062009 |
| signal transducer activity | 0.29313054064574 | bayes_pls_golite062009 |
| molecular transducer activity | 0.29313054064574 | bayes_pls_golite062009 |
| catalytic activity | 0.257477082550163 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase signaling protein activity | 0.17825540288715 | bayes_pls_golite062009 |
| transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity | 0.0594594490862095 | bayes_pls_golite062009 |
| SMAD binding | 0.0575833066764297 | bayes_pls_golite062009 |
| transcription repressor activity | 0.0382922567397515 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.0268350196675502 | bayes_pls_golite062009 |
