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View Structure Prediction Details

Protein: mig-5
Organism: Caenorhabditis elegans
Length: 666 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mig-5.

Description E-value Query
Range
Subject
Range
mig-5 - presynaptic density protein (PSD-95) repeat-like domain status:Confirmed UniProt:Q95ZQ0 protein_id:C...
431.0 [0..1] [666..1]

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Predicted Domain #1
Region A:
Residues: [1-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPPCTSDCS QIKVFYYLDD ETTPYVSVIE AREGVATLGN FKNSFTKRGY KYYAKELDPD  60
   61 IQREVKVELT TDSDRLRKSQ NGFYEIFLVS T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1wspA
Description: Crystal structure of axin dix domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [92-406]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGYGTLPRNS GTMTRPQRTA LDKRRRRSAD FDATPYSDAS LAPSTIVSRR AGEHLAELYT  60
   61 SNSEDPYQYD EHTRRTGDDS SLYEPLAARD MNKIYDDDRR RKKQKKERFR RPYVPSTISS 120
  121 ATESSVNSGL PRILEIYLPM KNVPYLGLSV CTIDGHIFVS EIAPEGAVEK DGRVNVGDQI 180
  181 LQVNRVSFEE LSGPQAVRSL REAASSKRPI TLYISKFARG APSEYDDPLA SMASETMPLD 240
  241 VGVWVETAVQ NTEKMKALGL DPQEQTATTI DDGTLPFTST ASDDEERMLY DQRRNGIPRA 300
  301 LIEEAERKRE NEQNE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.522879
Match: 1z87A
Description: solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [407-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIEQLTEMID PIIVVRSMAR PDSGLAVKNR KWLKILVPMS FIGRDLVDWL VDHMADIHNR  60
   61 KKARIYAARL LAAGLIRHVV SKLTFTEKCY YVFGDGILGN DRNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.0
Match: 1fshA
Description: Segment polarity protein Dishevelled-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.04426015975991 bayes_pls_golite062009
binding 1.99063774159045 bayes_pls_golite062009
DNA binding 1.63968725174405 bayes_pls_golite062009
nucleic acid binding 1.51035375793093 bayes_pls_golite062009
transcription factor activity 1.16072080355661 bayes_pls_golite062009
transcription activator activity 0.14130464856269 bayes_pls_golite062009
sequence-specific DNA binding 0.13573040816325 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [511-666]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDTTGTSGTT MRVEATTEVT YVGSPAPHAL AARVGRNIPH RLETTTLSPV AHDQTWLRRR  60
   61 RDCESPMTND YASMVGESQI GMNPVGNYHV FGTKNNHRQV PAPSQVTSSS LTNVTNSRKW 120
  121 WLRRPSADSS IQYYGSSSFS DSVAERSQPR FRRGEQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle